Evidence map›Paper›PMID 29630695›Full record

ArticleJAMA internal medicine2018

Dialysis Initiation and Mortality Among Older Veterans With Kidney Failure Treated in Medicare vs the Department of Veterans Affairs.

Manjula Kurella Tamura, I-Chun Thomas, Maria E Montez-Rath, Kristopher Kapphahn, Manisha Desai, Randall C Gale, Steven M Asch

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in JAMA internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. VA-Based Peritoneal Dialysis Program Feasibility Considerations and Process Outline.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2023
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  16. Medical Record Documentation of Goals-of-Care Discussions Among Older Veterans With Incident Kidney Failure.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020
    Article
  17. Article
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  19. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Manjula Kurella TamuraGeriatric Research and Education Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, California.
I-Chun ThomasGeriatric Research and Education Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, California.
Maria E Montez-RathDivision of Nephrology, Stanford University School of Medicine, Palo Alto, California.
Kristopher KapphahnQuantitative Sciences Unit, Stanford University School of Medicine, Palo Alto, California.
Manisha DesaiQuantitative Sciences Unit, Stanford University School of Medicine, Palo Alto, California.
Randall C GaleCenter for Innovation to Implementation, Veterans Affairs Palo Alto Health Care System, Palo Alto, California.
Steven M AschCenter for Innovation to Implementation, Veterans Affairs Palo Alto Health Care System, Palo Alto, California.
Stanford University · USStanford Medicine · USVA Palo Alto Health Care System · US

Funding

Stanford Islet Research CoreP30DK116074 · NIDDK · STANFORD UNIVERSITY · PI Seung K Kim · 2017 to 2026
$19.5M
HSRD VA I01 HX001262NIDDK NIH HHS P30 DK116074
6 · The paper itself

Abstract

Importance: The benefits of maintenance dialysis for older adults with end-stage renal disease (ESRD) are uncertain. Whether the setting of pre-ESRD nephrology care influences initiation of dialysis and mortality is not known. Objective: To compare initiation of dialysis and mortality among older veterans with incident kidney failure who received pre-ESRD nephrology care in fee-for-service Medicare vs the Department of Veterans Affairs (VA). Design, Setting, and Participants: Retrospective cohort study of patients from the US Medicare and VA health care systems evaluated 11 215 veterans aged 67 years or older with incident kidney failure between January 1, 2008, and December 31, 2011. Data analysis was performed March 15, 2016, through September 20, 2017. Exposures: Pre-ESRD nephrology care in Medicare vs VA health care systems. Main Outcome and Measures: Dialysis treatment and death within 2 years. Results: Of the 11 215 patients included in the study, 11 085 (98.8%) were men; mean (SD) age was 79.1 (6.9) years. Within 2 years of incident kidney failure, 7071 (63.0%) of the patients started dialysis and 5280 (47.1%) died. Patients who received pre-ESRD nephrology care in Medicare were more likely to undergo dialysis compared with patients who received pre-ESRD nephrology care in VA (82% vs 53%; adjusted risk difference, 28 percentage points; 95% CI, 26-30 percentage points). Differences in dialysis initiation between Medicare and VA were more pronounced among patients aged 80 years or older and patients with dementia or metastatic cancer, and less pronounced among patients with paralysis (P < .05 for interaction). Two-year mortality was higher for patients who received pre-ESRD care in Medicare compared with VA (53% vs 44%; adjusted risk difference, 5 percentage points; 95% CI, 3-7 percentage points). The findings were similar in a propensity-matched analysis. Conclusions and Relevance: Veterans who receive pre-ESRD nephrology care in Medicare receive dialysis more often yet are also more likely to die within 2 years compared with those in VA. The VA's integrated health care system and financing appear to favor lower-intensity treatment for kidney failure in older patients without a concomitant increase in mortality.

Indexed as

VeteransAgedAged, 80 and overFemaleHumansKidney Failure, ChronicMaleMedicareRenal DialysisRetrospective StudiesRisk FactorsSurvival AnalysisUnited StatesUnited States Department of Veterans Affairs

Identifiers

PMID29630695
PMCPMC6583073
OpenAlexW2796567272

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.