Evidence map›Paper›PMID 29629375›Full record

ArticleJournal of diabetes research2018

Arterial Stiffness Is Associated with Peripheral Sensory Neuropathy in Diabetes Patients in Ghana.

Kwame Yeboah, Jennifer A Agyekum, Richard N A Owusu Mensah, Patrick K Affrim, Linda Adu-Gyamfi, Rita O Doughan, Afua B Adjei

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Observational
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kwame YeboahDepartment of Physiology, School of Biomedical & Allied Health Sciences, University of Ghana, Accra, Ghana.ORCID 0000-0001-5240-0645
Jennifer A AgyekumDepartment of Medical Laboratory Sciences, School of Biomedical & Allied Health Sciences, University of Ghana, Accra, Ghana.
Richard N A Owusu MensahDepartment of Physiology, School of Biomedical & Allied Health Sciences, University of Ghana, Accra, Ghana.
Patrick K AffrimDepartment of Chemical Pathology, School of Biomedical & Allied Health Sciences, University of Ghana, Accra, Ghana.
Linda Adu-GyamfiDepartment of Medical Biochemistry, School of Biomedical & Allied Health Sciences, University of Ghana, Accra, Ghana.
Rita O DoughanDepartment of Physiology, School of Biomedical & Allied Health Sciences, University of Ghana, Accra, Ghana.
Afua B AdjeiDepartment of Chemical Pathology, School of Biomedical & Allied Health Sciences, University of Ghana, Accra, Ghana.
University of Ghana · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePeripheral sensory neuropathy (PSN) is among microvascular complications of diabetes that make patients prone to ulceration and amputation. Arterial stiffness is a predictor of cardiovascular diseases and microvascular complications associated with diabetes. We investigated the association between PSN and arterial stiffness, measured as aortic pulse wave velocity (PWVao) and cardio-ankle vascular index (CAVI).

methodIn a case-control design, arterial stiffness was measured in 240 diabetes patients and 110 nondiabetic control. Large-fibre nerve function was assessed by vibration perception threshold (VPT) using a neurothesiometer. PSN was defined as the VPT > 97.5th percentile from age- and gender-adjusted models in nondiabetic controls.

resultsThe overall prevalence of PSN was 16.6% in the entire study participants. Compared to non-PSN participants, PSN patients had higher levels of PWVao (9.5 ± 1.7 versus 8.7 ± 1.2 m/s,

conclusionPWVao and CAVI were associated with VPT and PSN in diabetes patients in Ghana. Patients having PSN have increased odds of CAVI, independent of other conventional risk factors.

Indexed as

AdultAgedAnkle Brachial IndexAortaCase-Control StudiesDiabetic NeuropathiesFemaleGhanaHumansMaleMiddle AgedPeripheral Nervous System DiseasesPulse Wave AnalysisVascular Stiffness

Identifiers

PMID29629375
PMCPMC5830981
OpenAlexW2788206173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.