Evidence map›Paper›PMID 29629168›Full record

ArticleChemical science2018

Hydrogen peroxide-triggered gene silencing in mammalian cells through boronated antisense oligonucleotides.

Shohei Mori, Kunihiko Morihiro, Takumi Okuda, Yuuya Kasahara, Satoshi Obika

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 54 citations in OpenAlex.

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  5. Amplified Production of a DNA Decoy Catalyzed by Intracellular MicroRNA.Angewandte Chemie (International ed. in English) · 2025
    Article
  6. Frosted DNA: β-Galactosidase Control of Oligonucleotide Activity.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  7. 2'-Nucleic acid therapeutics · 2022
    Article
  8. Article
  9. Conditionally Activated ("Caged") Oligonucleotides.Molecules (Basel, Switzerland) · 2021
    Review
  10. Article
  11. Caspase-Activated Oligonucleotide Probe.Bioconjugate chemistry · 2020
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shohei MoriGraduate School of Pharmaceutical Sciences , Osaka University , 1-6 Yamadaoka , Suita , Osaka 565-0871 , Japan . Email: morihiro@bioorg.rcast.u-tokyo.ac.jp ; Email: obika@phs.osaka-u.ac.jp.
Kunihiko MorihiroGraduate School of Pharmaceutical Sciences , Osaka University , 1-6 Yamadaoka , Suita , Osaka 565-0871 , Japan . Email: morihiro@bioorg.rcast.u-tokyo.ac.jp ; Email: obika@phs.osaka-u.ac.jp.
Takumi OkudaGraduate School of Pharmaceutical Sciences , Osaka University , 1-6 Yamadaoka , Suita , Osaka 565-0871 , Japan . Email: morihiro@bioorg.rcast.u-tokyo.ac.jp ; Email: obika@phs.osaka-u.ac.jp.
Yuuya KasaharaGraduate School of Pharmaceutical Sciences , Osaka University , 1-6 Yamadaoka , Suita , Osaka 565-0871 , Japan . Email: morihiro@bioorg.rcast.u-tokyo.ac.jp ; Email: obika@phs.osaka-u.ac.jp.
Satoshi ObikaGraduate School of Pharmaceutical Sciences , Osaka University , 1-6 Yamadaoka , Suita , Osaka 565-0871 , Japan . Email: morihiro@bioorg.rcast.u-tokyo.ac.jp ; Email: obika@phs.osaka-u.ac.jp.ORCID 0000-0002-6842-6812
National Institute of Biomedical Innovation, Health and Nutrition · JPSuita Municipal Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen peroxide (H

Identifiers

PMID29629168
PMCPMC5875086
OpenAlexW2774133663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.