ArticleNutrition research and practice2018
Protective effects of perilla oil and alpha linolenic acid on SH-SY5Y neuronal cell death induced by hydrogen peroxide.
Article in Nutrition research and practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 29 citations in OpenAlex.
- Standardization of Germinated Oat Extracts and Their Neuroprotective Effects Against AβMolecules (Basel, Switzerland) · 2025Article
- Effect of Pimecrolimus on apoptotic pathways in HToxicology research · 2025Article
- Article
- The Extract ofFoods (Basel, Switzerland) · 2023Article
- Characterization and functional analysis ofFrontiers in plant science · 2023Article
- Review
- Perilla pomace obtained from four different varieties have different levels and types of polyphenols and anti-allergic activity.Cytotechnology · 2022Article
- Dietary flaxseed's protective effects on body tissues of mice after oral exposure to xylene.Saudi journal of biological sciences · 2021Article
- Radioprotective effects of centipedegrass extract on NIH-3T3 fibroblasts via anti-oxidative activity.Experimental and therapeutic medicine · 2021Article
- Analgesic, anti-inflammatory and anti-ulcer properties of Thai Perilla frutescence fruit oil in animals.Bioscience reports · 2021Article
- Anacardium Occidentale L. Leaf Extracts Protect Against Glutamate/HFrontiers in pharmacology · 2021Article
- Effect of vegetable oils with different fatty acid composition on high-fat diet-induced obesity and colon inflammation.Nutrition research and practice · 2020Article
- Oxidized Perilla and Linseed Oils Induce Neuronal Apoptosis by Caspase-Dependent and -Independent Pathways.Foods (Basel, Switzerland) · 2020Article
- Twelve-month Studies onFoods (Basel, Switzerland) · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectiveOxidative stress plays a key role in neuronal cell damage, which is associated with neurodegenerative disease. The aim of present study was to investigate the neuroprotective effects of perilla oil (PO) and its active component, alpha-linolenic acid (ALA), against hydrogen peroxide (H MATERIALS/
methodsThe SH-SY5Y human neuroblastoma cells exposed to 250 µM H
resultsTreatment of H
conclusionsPO and its main fatty acid, ALA, exerted the protective activity from neuronal oxidative stress induced by H
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.