ArticleCancer nanotechnology2018
Antiangiogenic and antiapoptotic effects of green-synthesized zinc oxide nanoparticles using
Article in Cancer nanotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed.
- Orange Peel-Mediated Co-formation of a ZnO-Calcite Mixed-Phase Nanostructured Material: Physicochemical Characterization and Preliminary In vitro Antioxidant, α-Glucosidase Inhibitory, and Differential Cytotoxicity Assessment.Cell biochemistry and biophysics · 2026Article
- Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models.Advanced healthcare materials · 2026Review
- Marine Algae as Sustainable Platforms for the Green Synthesis of Metal Nanoparticles.ACS omega · 2026Review
- Sustainable development of novel zinc oxide nano flowers mediated red yeast rice for control of hepatocellular carcinoma.Scientific reports · 2026Article
- Marine Macroalgal Polysaccharides in Nanomedicine: Blue Biotechnology Contributions in Advanced Therapeutics.Molecules (Basel, Switzerland) · 2026Review
- Advancements in Neonatal Brain Injury Treatment: Nanomedicine-Based Strategies.International journal of nanomedicine · 2026Review
- Green Synthesis of Zinc Oxide Nanoparticles and Their Application in Anticancer Drug Delivery - A Review.International journal of nanomedicine · 2026Review
- The potential of Eco-friendly synthesis of multifunctional ZnO-CuO nanocomposites using Mentha longifolia extract for their biomedical applications.Journal of materials science. Materials in medicine · 2025Article
- Orange Peel-Mediated Green Synthesis of ZnO and CuO Nanoparticles: Evaluation for Antimicrobial Activity and Biocompatibility in Tissue Engineering.International journal of molecular sciences · 2025Article
- Progress in Nanofluid Technology: From Conventional to Green Nanofluids for Biomedical, Heat Transfer, and Machining Applications.Nanomaterials (Basel, Switzerland) · 2025Review
- Investigating the neuroprotective properties of3 Biotech · 2025Article
- Green-synthesized zinc oxide nanoparticles using Echinops spinosus extract: A promising anticancer agent for hepatocellular carcinoma.PloS one · 2025Article
- Ultrasonic Coating of Poly(D,L-lactic acid)/Poly(lactic-co-glycolic acid) Electrospun Fibers with ZnO Nanoparticles to Increase Angiogenesis in the CAM Assay.Biomedicines · 2024Article
- Anti‑angiogenic and cytotoxic evaluation of green‑synthesized FeBiomedical reports · 2024Article
- Functionalized ZnO-Based Nanocomposites for Diverse Biological Applications: Current Trends and Future Perspectives.Nanomaterials (Basel, Switzerland) · 2024Review
- Green Synthesis of Zinc Oxide Nanoparticles: Preparation, Characterization, and Biomedical Applications - A Review.International journal of nanomedicine · 2024Review
- An Updated Insight into Phytomolecules and Novel Approaches used in the Management of Breast Cancer.Current drug targets · 2024Review
- The antioxidant, anti-angiogenic, and anticancer impact of chitosan-coated herniarin-graphene oxide nanoparticles (CHG-NPs).Heliyon · 2023Article
- Updates on Biogenic Metallic and Metal Oxide Nanoparticles: Therapy, Drug Delivery and Cytotoxicity.Pharmaceutics · 2023Review
- Biosynthesis of Nanoparticles from Various Biological Sources and Its Biomedical Applications.Molecules (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
backgroundAlgae are one of the natural materials used to green synthesis of nanoparticles. This method leads to minimize the toxicity of the chemical materials used to nanoparticle synthesis.
methodsIn this study, zinc oxide nanoparticles (ZnO NPs) synthesized by
resultsTrypan blue assay results demonstrate a concentration-dependent decrease in cell viability and MTT assay shows increased growth inhibition in time and dose-dependent manner. In addition, CAM assay confirmed the ability of ZnO NPs to inhibit angiogenesis, but chick morphology (both the CR and weight) was not changed. Apoptotic tests (annexin V/PI and AO/PI) show that green-synthesized ZnO NPs induce apoptosis in all three time points (24, 48 and 72h).
conclusionsOur results confirm the beneficial cytotoxic effects of green-synthesized ZnO NPs on Human liver cancer cell. This nanoparticle decreased angiogenesis and induces apoptosis, so we conclude that these nanoparticles can be used as a supplemental drug in cancer treatments.
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