Evidence map›Paper›PMID 29628928›Full record

ArticleFrontiers in immunology2018

Impaired CD27

Fanlei Hu, Wei Zhang, Lianjie Shi, Xu Liu, Yuan Jia, Liling Xu, Huaqun Zhu, Yingni Li, Dakang Xu, Liwei Lu and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Immunological biomarkers of aging.Journal of immunology (Baltimore, Md. : 1950) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases.Clinical reviews in allergy & immunology · 2024
    Review
  14. Review
  15. Diminished LAG3Annals of medicine · 2023
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 3 countries.

Fanlei HuDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Wei ZhangDepartment of Rheumatology and Immunology, First Hospital Affiliated to Baotou Medical College, Inner Mongolia Key Laboratory of Autoimmunity, Baotou, China.
Lianjie ShiDepartment of Rheumatology and Immunology, Peking University International Hospital, Beijing, China.
Xu LiuDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Yuan JiaDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Liling XuDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Huaqun ZhuDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Yingni LiDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Dakang XuDepartment of Molecular and Translational Science, Faculty of Medicine, Hudson Institute of Medical Research, Monash University, Melbourne, VIC, Australia.
Liwei LuDepartment of Pathology, The University of Hong Kong, Hong Kong, Hong Kong.
Xiaoyan QiuDepartment of Immunology, School of Basic Medical Science, Peking University, Beijing, China.
Wanli LiuMOE Key Laboratory of Protein Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, School of Life Sciences, Institute for Immunology, Tsinghua University, Beijing, China.
Junjie QiaoDepartment of Orthopedics, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yongfu WangDepartment of Rheumatology and Immunology, First Hospital Affiliated to Baotou Medical College, Inner Mongolia Key Laboratory of Autoimmunity, Baotou, China.
Zhanguo LiDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Beijing, China.
Peking University · CNPeking University People's Hospital · CNBaotou Medical College · CNCapital Medical University · CNMonash University · AUTsinghua University · CNUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural antibodies, particularly natural IgM, are proved to play indispensable roles in the immune defenses against common infections. More recently, the protective roles of these natural IgM were also recognized in autoimmune diseases. They are mainly produced by B-1 and innate-like B cells (ILBs). Human CD19

Indexed as

AdultAgedAged, 80 and overArthritis, RheumatoidB-LymphocytesB-Lymphocyte SubsetsFemaleHumansImmunity, InnateImmunoglobulin DMaleMiddle AgedReceptors, Antigen, B-CellTranscriptomeTumor Necrosis Factor Receptor Superfamily, Member 7Immunoglobulin DReceptors, Antigen, B-CellTumor Necrosis Factor Receptor Superfamily, Member 7CD27+IgD+ B cellsgene signatureinnate-like B cellsnatural IgMrheumatoid arthritis

Identifiers

PMID29628928
PMCPMC5877504
OpenAlexW2794101317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.