Evidence map›Paper›PMID 29628794›Full record

ReviewContemporary oncology (Poznan, Poland)2018

Surface markers of cancer stem-like cells of ovarian cancer and their clinical relevance.

Aleksandra Klemba, J Karolina Purzycka-Olewiecka, Gabriel Wcisło, Anna M Czarnecka, Sławomir Lewicki, Bogdan Lesyng, Cezary Szczylik, Claudine Kieda

Abstract readReview
In one paragraph

Review in Contemporary oncology (Poznan, Poland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. EMT and cancer stem cells: Drivers of therapy resistance and promising therapeutic targets.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2025
    Review
  3. Article
  4. Article
  5. Cancer Stem Cells (CD44Journal of obstetrics and gynaecology of India · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Surprising magic of CD24 beyond cancer.Frontiers in immunology · 2023
    Review
  12. Review
  13. CD44Journal of the Egyptian National Cancer Institute · 2022
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aleksandra KlembaDepartment of Oncology, Military Institute of Medicine, Warsaw, Poland.
J Karolina Purzycka-OlewieckaDepartment of Oncology, Military Institute of Medicine, Warsaw, Poland.
Gabriel WcisłoDepartment of Oncology, Military Institute of Medicine, Warsaw, Poland.
Anna M CzarneckaDepartment of Oncology, Military Institute of Medicine, Warsaw, Poland.
Sławomir LewickiDepartment of Regenerative Medicine and Cell Biology, Military Institute of Hygiene and Epidemiology, Warsaw, Poland.
Bogdan LesyngFaculty of Physics, University of Warsaw, Poland.
Cezary SzczylikDepartment of Oncology, Military Institute of Medicine, Warsaw, Poland.
Claudine KiedaDepartment of Oncology, Military Institute of Medicine, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer stem-like cells (CSLCs) are defined as cancer cells with stem cell characteristics. Although CSLCs constitute no more than a few percent of the tumor mass, they play important roles in cancer chemo-resistance, metastasis and disease recurrence. Ovarian cancer (OC) is considered the most aggressive gynecological malignancy in which the role of CSLCs is of major significance, although it remains to be specified. The studies describing ovarian CSLC phenotype vary in the definition of the molecular pattern of expression of the main markers such as CD133, CD44, CD117, and CD24. Stem-like features of OC have been shown to correlate with the clinical course of the disease and permit diagnosis, prognosis and treatment outcome to be improved. Identification of CSLC markers could provide hallmarks which, related to the chemo-resistance of the disease, will facilitate treatment selection. This review describes recent advances in research on stem-like cell status in OC, mainly focusing on surface markers of CSLCs and their clinical relevance.

Indexed as

cancer stem-like cellsovarian cancerprognosissurface markers

Identifiers

PMID29628794
PMCPMC5885077

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.