Evidence map›Paper›PMID 29628780›Full record

ArticleGastrointestinal cancer : targets and therapy2018

Emerging treatment options for

Carling Ursem, Chloe E Atreya, Katherine Van Loon

Abstract read
In one paragraph

Article in Gastrointestinal cancer : targets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Binimetinib, Encorafenib, and Cetuximab Triplet Therapy for Patients WithJournal of clinical oncology : official journal of the American Society of Clinical Oncology · 2019
    Trial
  2. Review
  3. Review
  4. Review
  5. BRAFWorld journal of gastrointestinal oncology · 2021
    Article
  6. Review
  7. Molecular Oncology in Management of Colorectal Cancer.Indian journal of surgical oncology · 2021
    Article
  8. Article
  9. Journal of oncology · 2021
    Article
  10. BRAFJournal of experimental & clinical cancer research : CR · 2020
    Article
  11. Article
  12. An amino-terminalCold Spring Harbor molecular case studies · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Carling UrsemDivision of Hematology and Oncology, Department of Medicine, University of California, San Francisco, CA, USA.
Chloe E AtreyaDivision of Hematology and Oncology, Department of Medicine, University of California, San Francisco, CA, USA.
Katherine Van LoonDivision of Hematology and Oncology, Department of Medicine, University of California, San Francisco, CA, USA.

Funding

RESEARCH TRAINING IN GERIATRIC MEDICINET32AG000212 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 1991 to 2026
$7.7M
NIA NIH HHS T32 AG000212
6 · The paper itself

Abstract

The personalization of cancer care is rooted in the premise that there are subsets of patients with tumors harboring clinically relevant targets for patient-specific treatments. Colorectal cancer (CRC) is a disease that has historically been notable for its dearth of biomarkers that are predictive of response to targeted therapies. In recent years,

Indexed as

BRAF mutationcolon cancermolecular targetstargeted therapy

Identifiers

PMID29628780
PMCPMC5889076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.