ArticleJournal of conservative dentistry : JCD
Comparison of anti-bacterial efficiency of ibuprofen, diclofenac, and calcium hydroxide against
Article in Journal of conservative dentistry : JCD. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Trial
- Comparative antibacterial efficacy of calcium hydroxide, diclofenac sodium, chitosan, and boric acid against Enterococcus faecalis: an in vitro study.Scientific reports · 2026Article
- Zeolite-Y-Loaded Chitosan Nanoparticles as Endodontic Antimicrobial Agent: An In vitro Study.European journal of dentistry · 2026Article
- Efficacy of nonantimicrobial drugs againstJournal of conservative dentistry and endodontics · 2026Article
- Comparison of the Antibacterial Effect of Nano-calcium Hydroxide and Nano-chlorhexidine Against Enterococcus Faecalis : Short title: Antibacterial Effects of Nano-Calcium Hydroxide and Nano-CHX.Galen medical journal · 2026Article
- Anti-virulence effects of Diclofenac sodium in combination with gentamicin on Pseudomonas aeruginosa: attenuation of quorum sensing related traits and efflux pump systems.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Article
- Article
- Antibacterial and antibiofilm activities of diclofenac against levofloxacin-resistantIranian journal of microbiology · 2024Article
- Evaluation of minimum inhibitory concentration and minimum bactericidal concentration of royal jelly againstJournal of conservative dentistry and endodontics · 2024Article
- Antibacterial Effects of Erbium Chromium Laser along with/without Silver Nanoparticles in Root Canals Infected byInternational journal of dentistry · 2021Article
- Assessment of Nitrofurantoin as an Experimental Intracanal Medicament in Endodontics.BioMed research international · 2020Article
- Comparative evaluation of antibacterial efficacy of nonsteroidal anti-inflammatory medications and proton-pump inhibitor againstJournal of conservative dentistry : JCDArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextOne of the important goals of root canal therapy is disinfection aided by irrigation and intracanal medicaments. Commonly used nonsteroidal anti-inflammatory agents have shown anti-bacterial activity, thus, when used as intracanal medicaments, nonantibiotic agents have the potential to provide anti-inflammatory, local analgesic, and anti-bacterial activity.
aimThe aim of this study is to evaluate and compare the anti-bacterial efficiency of anti-inflammatory nonantibiotics ibuprofen and diclofenac, and routinely used intracanal dressing calcium hydroxide (Ca[OH] MATERIALS AND
methodsA total of 76 single-rooted mandibular premolar teeth were decoronated and instrumented up to F4-ProTaper rotary. Apical foramen was sealed with composite resin, and all external surfaces made impermeable with nail varnish, except for coronal access. Roots were autoclaved (121°C for 20 min), placed in Eppendorf tubes, and contaminated with
resultsWithin the limitations of the study, anti-inflammatory nonantibiotics (ibuprofen; diclofenac) were shown to have anti-bacterial effect against
conclusionSince nonsteroidal anti-inflammatory drugs (NSAIDs) have an anti-bacterial effect, it is possible to replace Ca(OH)
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.