Evidence map›Paper›PMID 29628442›Full record

ArticleJournal of lipid research2018

Obstructive sleep apnea and effects of continuous positive airway pressure on triglyceride-rich lipoprotein metabolism.

Luciano F Drager, Thauany M Tavoni, Vanessa M Silva, Raul D Santos, Rodrigo P Pedrosa, Luiz A Bortolotto, Carmen G Vinagre, Vsevolod Y Polotsky, Geraldo Lorenzi-Filho, Raul C Maranhao

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 80 citations in OpenAlex.

  1. Trial
  2. The mediating role of remnant cholesterol in the association between obstructive sleep apnea and diabetes: insights from two independent datasets.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  3. Article
  4. Article
  5. Association of ethylene oxide exposure and obstructive sleep apnea.Environmental health and preventive medicine · 2025
    Article
  6. Review
  7. Review
  8. Observational
  9. Article
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  13. Article
  14. Review
  15. Obesity and Obstructive Sleep Apnea.Handbook of experimental pharmacology · 2022
    Article
  16. Article
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  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Luciano F DragerHypertension Unit, University of Sao Paulo Medical School, São Paulo, Brazil.
Thauany M TavoniLaboratory of Metabolism and Lipids, University of Sao Paulo Medical School, São Paulo, Brazil.
Vanessa M SilvaLaboratory of Metabolism and Lipids, University of Sao Paulo Medical School, São Paulo, Brazil.
Raul D SantosLipid Clinic, University of Sao Paulo Medical School, São Paulo, Brazil.
Rodrigo P PedrosaSleep and Heart Laboratory, University of Pernambuco, Recife, Brazil.
Luiz A BortolottoHypertension Unit, University of Sao Paulo Medical School, São Paulo, Brazil.
Carmen G VinagreLaboratory of Metabolism and Lipids, University of Sao Paulo Medical School, São Paulo, Brazil.
Vsevolod Y PolotskyDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Geraldo Lorenzi-FilhoSleep Laboratory, Pulmonary Division, Heart Institute (InCor), University of Sao Paulo Medical School, São Paulo, Brazil.
Raul C MaranhaoLaboratory of Metabolism and Lipids, University of Sao Paulo Medical School, São Paulo, Brazil; Faculty of Pharmaceutical Sciences, University of Sao Paulo, São Paulo, Brazil. Electronic address: ramarans@usp.br.
Universidade de São Paulo · BRJohns Hopkins University · USUniversidade de Pernambuco · BR

Funding

Melanocortin 4 signaling in the carotid body in obesityR01HL133100 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Vsevolod Y Polotsky, Wan-yee Tang · 2016 to 2026
$7.1M
Treatment of Sleep Apnea by Targeting Leptin SignalingR01HL128970 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MENDELOWITZ, DAVID, POLOTSKY, VSEVOLOD Y · 2015 to 2023
$5.4M
Multi-Institutional Training in Genetic/Genomic Approaches to Sleep DisordersT32HL110952 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHERVIN, RONALD D, MIGNOT, EMMANUEL J · 2013 to 2022
$5.0M
Sleep Apnea and Dysregulation of Lipid MetabolismR01HL080105 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI POLOTSKY, VSEVOLOD Y · 2005 to 2014
$3.4M
NHLBI NIH HHS R01 HL080105NHLBI NIH HHS R01 HL133100NHLBI NIH HHS T32 HL110952
6 · The paper itself

Abstract

This study aimed to explore lipoprotein metabolism in obstructive sleep apnea (OSA) and the effects of continuous positive airway pressure (CPAP). We studied 15 men with severe OSA [apnea-hypopnea index (AHI) ≥30 events/hour] and 12 age-, BMI-, and waist circumference-matched volunteers without OSA (AHI <5 events/hour). Carotid intima-media thickness (CIMT) was determined by a blind examiner. After 12 h fasting, a triglyceride-rich chylomicron-like emulsion, labeled with [

Indexed as

Continuous Positive Airway PressureAdultFemaleHumansLipolysisLipoproteinsMaleSleepSleep Apnea, ObstructiveTriglyceridesLipoproteinslipoprotein triglycerideTriglyceridescardiovascular diseaseschylomicron remnantschylomicronsclinical studieslipid and lipoprotein metabolismlipoprotein kineticspostprandial lipidemia

Identifiers

PMID29628442
PMCPMC5983397
OpenAlexW2795844634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.