Evidence map›Paper›PMID 29628198›Full record

ReviewTrends in neurosciences2018

Slow-Wave Activity Enhancement to Improve Cognition.

Kristine A Wilckens, Fabio Ferrarelli, Matthew P Walker, Daniel J Buysse

Abstract readReview
In one paragraph

Review in Trends in neurosciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kristine A WilckensUniversity of Pittsburgh School of Medicine, Department of Psychiatry, Pittsburgh, PA, USA. Electronic address: wilckenska@upmc.edu.
Fabio FerrarelliUniversity of Pittsburgh School of Medicine, Department of Psychiatry, Pittsburgh, PA, USA.
Matthew P WalkerUniversity of California, Berkeley, Department of Psychology, CA, USA.
Daniel J BuysseUniversity of Pittsburgh School of Medicine, Department of Psychiatry, Pittsburgh, PA, USA.

Funding

Tau pathology, sleep disruption, and hippocampal memory decline in older adultsRF1AG054106 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI WALKER, MATTHEW P · 2017 to 2018
$4.7M
Sleep Loss, Human Memory and Brain Plasticity across the LifespanR01AG031164 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI WALKER, MATTHEW P · 2008 to 2019
$4.7M
A sleep electroencephalography biomarker predicting Alzheimer's disease pathologyRF1AG054019 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI WALKER, MATTHEW P · 2016 to 2016
$4.1M
Anxiety, sleep disruption and emotional brain dysregulationR01MH093537 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI WALKER, MATTHEW P · 2012 to 2016
$1.6M
Slow-wave sleep and executive network function in older adultsK01AG049879 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WILCKENS, KRISTINE ANN · 2016 to 2020
$713k
NIA NIH HHS K01 AG049879NIA NIH HHS R01 AG031164NIA NIH HHS RF1 AG054019NIA NIH HHS RF1 AG054106NIMH NIH HHS R01 MH093537
6 · The paper itself

Abstract

Slow-wave activity (SWA), and its coupling with other sleep features, reorganizes cortical circuitry, supporting cognition. This raises the question: can cognition be improved through SWA enhancement? SWA enhancement techniques range from behavioral interventions (such as exercise), which have high feasibility but low specificity, to laboratory-based techniques (such as transcranial stimulation), which have high specificity but are less feasible for widespread use. In this review we describe the pathways through which SWA is enhanced. Pathways encompass enhanced neural activity, increased energy metabolism, and endocrine signaling during wakefulness; also direct enhancement during sleep. We evaluate the robustness and practicality of SWA-enhancement techniques, discuss approaches for determining a causal role of SWA on cognition, and present questions to clarify the mechanisms of SWA-dependent cognitive improvements.

Indexed as

AnimalsCognitionCognitive DysfunctionHumansSleep Stagesexecutive functionmemory consolidationNREM sleepslow-wave activity

Identifiers

PMID29628198
PMCPMC6015540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.