ArticleNeuron2018
Amygdala Functional and Structural Connectivity Predicts Individual Risk Tolerance.
Article in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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Who cites it
48 citing papers in PubMed.
- Histamine HMolecular psychiatry · 2026Article
- Electrophysiological dissociation of human posterior cingulate cortex contributions to value- and memory-based decision-making.bioRxiv : the preprint server for biology · 2026Article
- Modeling information demand in the framework of probabilistic reasoning.Communications psychology · 2026Article
- Pathfinding: a neurodynamical account of intuition.Communications biology · 2025Review
- The role of the ventral striatum in the relationship between impulsive decision-making and emotional self-regulation by cognitive reappraisal.Scientific reports · 2025Article
- Neural Processes Linking Interoception to Moral Preferences Aligned with Group Consensus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Social Risk Coding by Amygdala Activity and Connectivity with the Dorsal Anterior Cingulate Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Sex differences in sensitivity to dopamine receptor manipulations of risk-based decision making in rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Functional brain network properties correlate with individual risk tolerance in young adults.Heliyon · 2024Article
- Multivariate analysis of multimodal brain structure predicts individual differences in risk and intertemporal preference.bioRxiv : the preprint server for biology · 2024Article
- The neurocomputational link between defensive cardiac states and approach-avoidance arbitration under threat.Communications biology · 2024Article
- Brain volumes, behavioral inhibition, and anxiety disorders in children: results from the adolescent brain cognitive development study.BMC psychiatry · 2024Article
- Dorsal and ventral fronto-amygdala networks underlie risky decision-making in age-related cognitive decline.GeroScience · 2024Article
- Reduced cortical complexity in ventromedial prefrontal cortex is associated with a greater preference for risky and immediate rewards.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Structural projections to the nucleus accumbens link to impulsive components of human risk preference.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Effects of acute stress and depression on functional connectivity between prefrontal cortex and the amygdala.Molecular psychiatry · 2023Article
- Anatomical and Functional Connectivity of Critical Deep Brain Structures and Their Potential Clinical Application in Brain Stimulation.Journal of clinical medicine · 2023Article
- The composition of the choice set modulates probability weighting in risky decisions.Cognitive, affective & behavioral neuroscience · 2023Article
- Internet gaming disorder and tobacco use disorder share neural connectivity patterns between the subcortical and the motor network.Human brain mapping · 2023Article
- Not all bad decisions are alike: approach and avoidant bad decisions are associated with distinct network organization.Frontiers in neuroscience · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Risk tolerance, the degree to which an individual is willing to tolerate risk in order to achieve a greater expected return, influences a variety of financial choices and health behaviors. Here we identify intrinsic neural markers for risk tolerance in a large (n = 108) multimodal imaging dataset of healthy young adults, which includes anatomical and resting-state functional MRI and diffusion tensor imaging. Using a data-driven approach, we found that higher risk tolerance was most strongly associated with greater global functional connectivity (node strength) of and greater gray matter volume in bilateral amygdala. Further, risk tolerance was positively associated with functional connectivity between amygdala and medial prefrontal cortex and negatively associated with structural connectivity between these regions. These findings show how the intrinsic functional and structural architecture of the amygdala, and amygdala-medial prefrontal pathways, which have previously been implicated in anxiety, are linked to individual differences in risk tolerance during economic decision making.
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Registered trials
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