Evidence map›Paper›PMID 29627876›Full record

ArticleMolecular neurobiology2018

Naringin Attenuates Cerebral Ischemia-Reperfusion Injury Through Inhibiting Peroxynitrite-Mediated Mitophagy Activation.

Jinghan Feng, Xingmiao Chen, Shengwen Lu, Wenting Li, Dan Yang, Weiwei Su, Xijun Wang, Jiangang Shen

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 106 citations in OpenAlex.

  1. Review
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  7. [Nitrosative stress promotes the malignant biological behavior of breast cancer through the glycolytic pathway].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
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  19. Metabolomics: A useful tool for ischemic stroke research.Journal of pharmaceutical analysis · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jinghan FengSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Room 110, 1/F, No.10, Sassoon Road, Pokfulam, Hong Kong, SAR, China.
Xingmiao ChenSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Room 110, 1/F, No.10, Sassoon Road, Pokfulam, Hong Kong, SAR, China.
Shengwen LuNational TCM Key Laboratory of Serum Pharmacochemistry, Key Lab of Chinmedomics, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese Medicine, Harbin, China.
Wenting LiSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Room 110, 1/F, No.10, Sassoon Road, Pokfulam, Hong Kong, SAR, China.
Dan YangMorningside Laboratory for Chemical Biology and Department of Chemistry, The University of Hong Kong, Hong Kong, SAR, China.
Weiwei SuGuangzhou Quality R&D Center of Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Xijun WangNational TCM Key Laboratory of Serum Pharmacochemistry, Key Lab of Chinmedomics, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese Medicine, Harbin, China. xijunw@sina.com.
Jiangang ShenSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Room 110, 1/F, No.10, Sassoon Road, Pokfulam, Hong Kong, SAR, China. shenjg@hku.hk.ORCID http://orcid.org/0000-0002-4199-8095
Chinese University of Hong Kong · HKHeilongjiang University of Chinese Medicine · CNSun Yat-sen University · CNUniversity of Hong Kong · HK

Funding

Areas of Excellence Scheme 2016/17 AoE/P-705/16National Natural Science Foundation of China 31570855Research Grants Council, University Grants Committee 17102915Research Grants Council, University Grants Committee 17118717
6 · The paper itself

Abstract

Excessive autophagy/mitophagy plays important roles during cerebral ischemia-reperfusion (I/R) injury. Peroxynitrite (ONOO

Indexed as

MitophagyAnimalsBlood-Brain BarrierBrain IschemiaCell Line, TumorCell SurvivalFlavanonesHumansMaleNADPH OxidasesNitric OxideOxygenPeroxynitrous AcidRats, Sprague-DawleyReperfusion InjuryTyrosine3-nitrotyrosineFlavanonesNADPH OxidasesnaringinNitric OxideOxygenPeroxynitrous AcidTyrosineCerebral ischemia-reperfusion injuryMitophagyNaringinNitrative stressPeroxynitrite

Identifiers

PMID29627876
OpenAlexW2795804044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.