Evidence map›Paper›PMID 29627697›Full record

ArticlePsychiatry research2018

Are the components of social reciprocity transdiagnostic across pediatric neurodevelopmental disorders? Evidence for common and disorder-specific social impairments.

Alexandra Sturm, Michelle Rozenman, Susanna Chang, James J McGough, James T McCracken, John C Piacentini

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychiatry research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alexandra SturmSemel Institute for Neuroscience and Human Behavior, University of California, 760 Westwood Plaza, Rm 68-228B, Los Angeles, USA. Electronic address: asturm@mednet.ucla.edu.
Michelle RozenmanSemel Institute for Neuroscience and Human Behavior, University of California, 760 Westwood Plaza, Rm 68-228B, Los Angeles, USA.
Susanna ChangSemel Institute for Neuroscience and Human Behavior, University of California, 760 Westwood Plaza, Rm 68-228B, Los Angeles, USA.
James J McGoughSemel Institute for Neuroscience and Human Behavior, University of California, 760 Westwood Plaza, Rm 68-228B, Los Angeles, USA.
James T McCrackenSemel Institute for Neuroscience and Human Behavior, University of California, 760 Westwood Plaza, Rm 68-228B, Los Angeles, USA.
John C PiacentiniSemel Institute for Neuroscience and Human Behavior, University of California, 760 Westwood Plaza, Rm 68-228B, Los Angeles, USA.
Salk Institute for Biological Studies · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
Translational Research to Enhance Cognitive ControlP50MH077248 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCCRACKEN, JAMES T. · 2006 to 2011
$9.2M
UCLA Center for Translational Research in Neurodevelopment: UC-TRaNU54HD087101 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCCRACKEN, JAMES T. · 2016 to 2020
$6.5M
Development of a Personalized Attention Training Program for Pediatric OCDR34MH095885 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHANG, SUSANNA W. · 2012 to 2014
$608k
Characterization and Sequential Pharmacotherapy of Severe Mood DysregulationU01MH093582 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCGOUGH, JAMES JOHN · 2012 to 2013
$416k
NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1 TR001881NICHD NIH HHS U54 HD087101NIMH NIH HHS P50 MH077248NIMH NIH HHS R34 MH095885NIMH NIH HHS U01 MH093582
6 · The paper itself

Abstract

Deficits in social communication are a core feature of autism spectrum disorder (ASD), yet significant social problems have been observed in youth with many neurodevelopmental disorders. In this preliminary investigation, we aimed to explore whether domains of social reciprocity (i.e., social communication, social cognition, social awareness, social motivation, and restricted and repetitive behaviors) represent transdiagnostic traits. These domains were compared across youth ages 7-17 with obsessive-compulsive disorder (OCD; N = 32), tic disorders (TD; N = 20), severe mood dysregulation (N = 33) and autism spectrum disorder (N = 35). While the ASD group was rated by parents as exhibiting the greatest social reciprocity deficits across domains, a high proportion of youth with severe mood dysregulation also exhibited pronounced deficits in social communication, cognition, and awareness. The ASD and severe mood dysregulation groups demonstrated comparable scores on the social awareness domain. In contrast, social motivation and restricted and repetitive behaviors did not appear to be transdiagnostic domains in severe mood dysregulation, OCD, or TD groups. The present work provides preliminary support that social awareness, and to a lesser extent social communication and cognition, may represent features of social reciprocity that are transdiagnostic across ASD and severe mood dysregulation.

Indexed as

Social BehaviorAdolescentAutism Spectrum DisorderChildDiagnosis, DifferentialFemaleHumansMaleMood DisordersObsessive-Compulsive DisorderParentsTic DisordersAdolescentAutism spectrum disorderChildNeurodevelopmental disordersSocial communicationSocial reciprocityTransdiagnostic

Identifiers

PMID29627697
PMCPMC6092937
OpenAlexW2794496803

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.