Evidence map›Paper›PMID 29627409›Full record

ArticleDrug and alcohol dependence2018

Marijuana use during and after pregnancy and association of prenatal use on birth outcomes: A population-based study.

Jean Y Ko, Van T Tong, Jennifer M Bombard, Donald K Hayes, John Davy, Katherine A Perham-Hester

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug and alcohol dependence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04422600 (Fetal Exposure to Cannabinoids), which is not on this map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
17.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04422600 completednot on this mapstarted 2020, after this paper: background citation

Fetal Exposure to Cannabinoids: Exposure, Methylation and Neurodevelopmental Effects

Typeobservational_patient_registrySponsorUniversity of ArkansasRan2020 to 2023Enrolled72ConditionsFetal Exposure Timing UnspecifiedArmsThere is no other intervention, only clinical treatment.
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jean Y KoDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS F74, Atlanta, GA, 30341, USA. Electronic address: JeanKo@cdc.gov.
Van T TongDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS F74, Atlanta, GA, 30341, USA.
Jennifer M BombardDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS F74, Atlanta, GA, 30341, USA.
Donald K HayesDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS F74, Atlanta, GA, 30341, USA; Hawaii Department of Health, 714-A Sunset Avenue, Room 109, Honolulu, HI, 96816, USA.
John DavyVermont Department of Health, 108 Cherry Street, Burlington, VT, 05402, USA.
Katherine A Perham-HesterAlaska Department of Health and Social Services, 3601C Street, Suite 358, Anchorage, AK, 99503, USA.
Centers for Disease Control and Prevention · USNational Center for Chronic Disease Prevention and Health Promotion · USAlaska Department of Health and Social Services · USVermont Department of Health · US

Funding

Intramural CDC HHS CC999999NCCDPHP CDC HHS U01 DP003137NCCDPHP CDC HHS U58 DP006002
6 · The paper itself

Abstract

backgroundWe sought to describe the correlates of marijuana use during and after pregnancy, and to examine the independent relationship between prenatal marijuana use and infant outcomes. STUDY

designWe used state-specific data from the Pregnancy Risk Assessment Monitoring System (N = 9013) to describe correlates of self-reported prenatal and postpartum marijuana use. We estimated differences in mean infant birth weight and gestational age among prenatal marijuana users and nonusers, controlling for relevant covariates (i.e., cigarette smoking).

resultsRespectively, 4.2% (95% CI: 3.8-4.7) and 6.8% (95% CI: 6.0-7.7) of women reported using marijuana during and after pregnancy. Compared to nonusers, prenatal marijuana users were more likely to be ≤24 years; non-Hispanic white, not married, have <12 years of education, have Medicaid/IHS/Other insurance, be on WIC during pregnancy, have annual household income <$20,000, cigarette smokers, and alcohol drinkers during pregnancy (p-values < 0.05). After adjustment, no differences in gestational age or birthweight were observed. Postpartum users were more likely to smoke cigarettes (48.7% vs. 20.3%), experience postpartum depressive symptoms (14.0% vs. 9.0%), and breastfeed for <8 weeks (34.9% vs. 18.1%).

conclusionCo-use of substances was common among prenatal and postpartum marijuana users. Prenatal marijuana use was not independently associated with lower average birthweight or gestational age. Postpartum marijuana use was associated with depressive symptoms and shorter breastfeeding duration. Surveillance of marijuana use among pregnant and postpartum women is critical to better understanding the relationship of marijuana use with birth outcomes, and postpartum experiences such as depression and breastfeeding.

Indexed as

AdultBirth WeightBreast FeedingDepression, PostpartumFemaleGestational AgeHumansInfantInfant, NewbornMarijuana AbusePostpartum PeriodPregnancyPregnancy ComplicationsYoung AdultLow birth weightMarijuanaPostpartumPregnancyPreterm

Identifiers

PMID29627409
PMCPMC7479809
OpenAlexW2794451470

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.