Evidence map›Paper›PMID 29627355›Full record

ReviewChest2018

Atrial Fibrillation in the ICU.

Nicholas A Bosch, Jonathan Cimini, Allan J Walkey

Open access · bronzeAbstract readReview
In one paragraph

Review in Chest, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 156 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
156citing papers in PubMed, 5 pooled it
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

156 citing papers in PubMed, 5 syntheses or guidelines pooled it, 273 citations in OpenAlex.

  1. Pooled it
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  6. Trial
  7. Clinical subtypes and prognosis of new-onset atrial fibrillation in critically ill patients.International journal of cardiology. Cardiovascular risk and prevention · 2026
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96 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nicholas A BoschDepartment of Medicine, The Pulmonary Center, Boston University School of Medicine, Boston, MA.
Jonathan CiminiMassachusetts College of Pharmacy and Health Sciences, Worcester Campus, Boston, MA.
Allan J WalkeyDepartment of Medicine, The Pulmonary Center, Boston University School of Medicine, Boston, MA; Center for Implementation and Improvement Sciences, Boston University School of Medicine, Boston, MA. Electronic address: alwalkey@bu.edu.
Boston University · USMCPHS University · US

Funding

BIOLOGY OF THE LUNG--MULTIDISCIPLINARY PROGRAMT32HL007035 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Darrell N. Kotton, JOSEPH P MIZGERD · 1985 to 2026
$24.3M
Automated detection and prediction of atrial fibrillation during sepsisR01HL136660 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WALKEY, ALLAN J. · 2017 to 2020
$2.2M
Atrial Fibrillation in Sepsis: Patient Outcomes and Provider Practice PatternsK01HL116768 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WALKEY, ALLAN J. · 2013 to 2017
$742k
NHLBI NIH HHS K01 HL116768NHLBI NIH HHS R01 HL136660NHLBI NIH HHS T32 HL007035
6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most common arrhythmia encountered in the ICU. Preexisting AF is highly prevalent among older patients with chronic conditions who are at risk for critical illness, whereas new-onset AF can be triggered by accelerated atrial remodeling and arrhythmogenic triggers encountered during critical illness. The acute loss of atrial systole and onset of rapid ventricular rates that characterize new-onset AF often lead to decreased cardiac output and hemodynamic compromise. Thus, new-onset AF is both a marker of disease severity as well as a likely contributor to poor outcomes, similar to other manifestations of organ dysfunction during critical illness. Evaluating immediate hemodynamic effects of new-onset AF during critical illness is an important component of rapid clinical assessment aimed at identifying patients in need of urgent direct current cardioversion, treatment of reversible inciting factors, and identification of patients who may benefit from pharmacologic rate or rhythm control. In addition to acute hemodynamic effects, new-onset AF during critical illness is associated with both short- and long-term increases in the risk of stroke, heart failure, and death, with AF recurrence rates of approximately 50% within 1 year following hospital discharge. In the absence of a strong evidence base, there is substantial practice variation in the choice of strategies for management of new-onset AF during critical illness. We describe acute and long-term evaluation and management strategies based on current evidence and propose future avenues of investigation to fill large knowledge gaps in the management of patients with AF during critical illness.

Indexed as

Atrial FibrillationCritical IllnessIntensive Care UnitsHumansPatient Care ManagementRisk Factorsatrial fibrillationcritical illnesssepsis

Identifiers

PMID29627355
PMCPMC6335260
OpenAlexW2796310473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.