Evidence map›Paper›PMID 29626611›Full record

Observational studyResuscitation2018

Preliminary observations in systemic oxygen consumption during targeted temperature management after cardiac arrest.

Amy Uber, Anne V Grossestreuer, Catherine E Ross, Parth V Patel, Ambica Trehan, Michael W Donnino, Katherine M Berg

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Resuscitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04211207 (Evaluation of the Heart's Respiratory Quotient as Predictive Value After Extra-hospital), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04211207 completednot on this mapstarted 2020, after this paper: background citation

Evaluation of the Heart's Respiratory Quotient as Predictive Value After Extra-hospital

TypeobservationalSponsorUniversity Hospital, GrenobleRan2020 to 2023Enrolled40ConditionsCardiac ArrestArmsnon invasive monitoring value
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Observational
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Looking for COJournal of the American Heart Association · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amy UberDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, 1 Deaconess Road, Boston, MA 02115, USA; Michigan State University College of Human Medicine, 15 Michigan Street NE, Grand Rapids, MI 49503, USA.
Anne V GrossestreuerDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, 1 Deaconess Road, Boston, MA 02115, USA.
Catherine E RossDivision of Medicine Critical Care, Department of Medicine, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.
Parth V PatelDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, 1 Deaconess Road, Boston, MA 02115, USA.
Ambica TrehanDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, 1 Deaconess Road, Boston, MA 02115, USA.
Michael W DonninoDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, 1 Deaconess Road, Boston, MA 02115, USA; Department of Medicine, Division of Critical Care, Beth Israel Deaconess Medical Center, 1 Deaconess Road, Boston, MA 02115, USA.
Katherine M BergDepartment of Medicine, Division of Critical Care, Beth Israel Deaconess Medical Center, 1 Deaconess Road, Boston, MA 02115, USA. Electronic address: kberg@bidmc.harvard.edu.

Funding

Harvard Clinical and Translational Science Center (UL1)UL1TR000170 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2012 to 2013
$31.4M
Thiamine As A Metabolic Resuscitator In Cardiac ArrestR01HL136705 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI DONNINO, MICHAEL WILLIAM · 2017 to 2021
$2.2M
Thaimine as an adjunct metabolic resuscitator in cardiac arrestK24HL127101 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI DONNINO, MICHAEL WILLIAM · 2015 to 2024
$1.2M
Thiamine v placebo to improve oxygen consumption after in-hospital cardiac arrestK23HL128814 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BERG, KATHERINE M · 2016 to 2021
$1.0M
NCATS NIH HHS UL1 TR000170NHLBI NIH HHS K23 HL128814NHLBI NIH HHS K24 HL127101NHLBI NIH HHS R01 HL136705
6 · The paper itself

Abstract

aimLimited data suggests low oxygen consumption (VO

methodsUsing a gas exchange monitor, we measured continuous VO

resultsIn 17 patients, VO

conclusionsThere was a significant association between VO

Indexed as

Oxygen ConsumptionPulmonary Gas ExchangeAgedAged, 80 and overArea Under CurveFemaleHeart ArrestHumansHypothermia, InducedMaleMiddle AgedMonitoring, PhysiologicProspective StudiesRespiration, ArtificialCardiopulmonary resuscitationCell respirationEnergy metabolismHeart arrestOxygen consumption

Identifiers

PMID29626611
PMCPMC6003666

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.