ArticleMolecular biology reports2018
Comparative in silico profiling of epigenetic modifiers in human tissues.
Article in Molecular biology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Altered Gene Expression Profiles in Neural Stem Cells Derived from Duchenne Muscular Dystrophy Patients with Intellectual Disability.Experimental neurobiology · 2021Article
- Epigenetic Alterations of Heat Shock Proteins (HSPs) in Cancer.International journal of molecular sciences · 2019Review
- Propionate of a microbiota metabolite induces cell apoptosis and cell cycle arrest in lung cancer.Molecular medicine reports · 2019Article
- Downregulation of PRMT1, a histone arginine methyltransferase, by sodium propionate induces cell apoptosis in colon cancer.Oncology reports · 2019Article
- SETDB1 regulates SMAD7 expression for breast cancer metastasis.BMB reports · 2019Article
- The novel prognostic marker, EHMT2, is involved in cell proliferation via HSPD1 regulation in breast cancer.International journal of oncology · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The technology of tissue differentiation from human pluripotent stem cells has attracted attention as a useful resource for regenerative medicine, disease modeling and drug development. Recent studies have suggested various key factors and specific culture methods to improve the successful tissue differentiation and efficient generation of human induced pluripotent stem cells. Among these methods, epigenetic regulation and epigenetic signatures are regarded as an important hurdle to overcome during reprogramming and differentiation. Thus, in this study, we developed an in silico epigenetic panel and performed a comparative analysis of epigenetic modifiers in the RNA-seq results of 32 human tissues. We demonstrated that an in silico epigenetic panel can identify epigenetic modifiers in order to overcome epigenetic barriers to tissue-specific differentiation.
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Registered trials
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