Evidence map›Paper›PMID 29626165›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Collagen XIII Is Required for Neuromuscular Synapse Regeneration and Functional Recovery after Peripheral Nerve Injury.

Zarin Zainul, Anne Heikkinen, Hennariikka Koivisto, Iina Rautalahti, Mika Kallio, Shuo Lin, Heli Härönen, Oula Norman, Markus A Rüegg, Heikki Tanila and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
  6. Review
  7. Article
  8. Article
  9. The application of collagen in the repair of peripheral nerve defect.Frontiers in bioengineering and biotechnology · 2022
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Neuromuscular Development and Disease: Learning FromFrontiers in cell and developmental biology · 2021
    Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. NMJ maintenance and repair in aging.Current opinion in physiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Zarin ZainulCenter for Cell-Matrix Research, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, 90014 Oulu, Finland.ORCID 0000-0002-9412-0964
Anne HeikkinenCenter for Cell-Matrix Research, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, 90014 Oulu, Finland.ORCID 0000-0001-9852-773X
Hennariikka KoivistoA.I. Virtanen Institute, University of Eastern Finland, 70211 Kuopio, Finland.
Iina RautalahtiA.I. Virtanen Institute, University of Eastern Finland, 70211 Kuopio, Finland.
Mika KallioDepartment of Clinical Neurophysiology, Oulu University Hospital, 90220 Oulu, Finland.ORCID 0000-0002-7908-9823
Shuo LinBiozentrum, University of Basel, CH-4056 Basel, Switzerland.ORCID 0000-0003-2317-0339
Heli HärönenCenter for Cell-Matrix Research, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, 90014 Oulu, Finland.ORCID 0000-0002-7305-5323
Oula NormanCenter for Cell-Matrix Research, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, 90014 Oulu, Finland.ORCID 0000-0002-2949-2024
Markus A RüeggBiozentrum, University of Basel, CH-4056 Basel, Switzerland.ORCID 0000-0002-4974-9384
Heikki TanilaA.I. Virtanen Institute, University of Eastern Finland, 70211 Kuopio, Finland.ORCID 0000-0001-8579-7562
Taina PihlajaniemiCenter for Cell-Matrix Research, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, 90014 Oulu, Finland, taina.pihlajaniemi@oulu.fi.ORCID 0000-0002-1664-9045
University of Oulu · FIUniversity of Eastern Finland · FIUniversity of Basel · CHOulu University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Collagen XIII occurs as both a transmembrane-bound and a shed extracellular protein and is able to regulate the formation and function of neuromuscular synapses. Its absence results in myasthenia: presynaptic and postsynaptic defects at the neuromuscular junction (NMJ), leading to destabilization of the motor nerves, muscle regeneration and atrophy. Mutations in

Indexed as

Nerve RegenerationAnimalsCollagen Type XIIIMaleMiceMice, Inbred C57BLNeuromuscular JunctionPeripheral Nerve InjuriesRecovery of FunctionCollagen Type XIIIagingcollagen XIIIneuromuscular junctionperipheral nerve injuryrecoveryregeneration

Identifiers

PMID29626165
PMCPMC6596032
OpenAlexW2795453562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.