Evidence map›Paper›PMID 29626125›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2018

Age-Related Change in 5-HT

Rajiv Radhakrishnan, Nabeel Nabulsi, Edward Gaiser, Jean-Dominique Gallezot, Shannan Henry, Beata Planeta, Shu-Fei Lin, Jim Ropchan, Wendol Williams, Evan Morris and 4 more

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  9. An Interactive Brain Atlas of Knowledge.bioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rajiv RadhakrishnanDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
Nabeel NabulsiDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut; and.
Edward GaiserDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
Jean-Dominique GallezotDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut; and.
Shannan HenryDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut; and.
Beata PlanetaDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut; and.
Shu-Fei LinDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut; and.
Jim RopchanDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut; and.
Wendol WilliamsDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
Evan MorrisDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut; and.
Deepak Cyril D'SouzaDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
Yiyun HuangDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut; and.
Richard E CarsonDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut; and.
David MatuskeyDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut david.matuskey@yale.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
6 · The paper itself

Abstract

Serotonin receptor 6 (5-hydroxytrypamine-6, or 5-HT

Indexed as

Healthy VolunteersPositron-Emission TomographyQuinolinesSulfonesAdultAgingHumansImage Processing, Computer-AssistedMaleMiddle AgedReceptors, SerotoninYoung AdultGSK215083QuinolinesReceptors, Serotoninserotonin 6 receptorSulfones11C-GSK2150835-HT6age effectsPET imagingserotonin 6

Identifiers

PMID29626125
PMCPMC6126437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.