Evidence map›Paper›PMID 29626089›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Stearic Acid Induces CD11c Expression in Proinflammatory Macrophages via Epidermal Fatty Acid Binding Protein.

Jun Zeng, Yuwen Zhang, Jiaqing Hao, Yanwen Sun, Shujun Liu, David A Bernlohr, Edward R Sauter, Margot P Cleary, Jill Suttles, Bing Li

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 43 citations in OpenAlex.

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  14. Regulation of macrophage functions by FABP-mediated inflammatory and metabolic pathways.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2021
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Fatty acid-binding proteins: functional understanding and diagnostic implications.Current opinion in clinical nutrition and metabolic care · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Jun ZengDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY 40202.
Yuwen ZhangDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY 40202.
Jiaqing HaoDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY 40202.ORCID 0000-0002-2834-7255
Yanwen SunDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY 40202.
Shujun LiuThe Hormel Institute, University of Minnesota, Austin, MN 55912.
David A BernlohrCollege of Biological Sciences, University of Minnesota, Minneapolis, MN 55455; and.ORCID 0000-0001-6969-9129
Edward R SauterHartford Healthcare Cancer Institute, Hartford, CT 06103.
Margot P ClearyThe Hormel Institute, University of Minnesota, Austin, MN 55912.
Jill SuttlesDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY 40202.
Bing LiDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY 40202; b.li@louisville.edu.
University of Louisville · USUniversity of Minnesota · USHartford Hospital · US

Funding

LIPID BINDING PROTEINS IN OBESITY/DIABETES SYNDROMESR01DK053189 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BERNLOHR, DAVID A · 1998 to 2020
$5.6M
Prevention of Breast Cancer Development by Epidermal Fatty Acid Binding Protein (R01CA180986 · NCI · UNIVERSITY OF MINNESOTA · PI LI, BING · 2014 to 2025
$3.3M
The role of adipocyte/macrophage fatty acid binding protein in breast cancer deveR01CA177679 · NCI · UNIVERSITY OF MINNESOTA · PI LI, BING · 2014 to 2018
$1.6M
NCI NIH HHS R01 CA177679NCI NIH HHS R01 CA180986NIDDK NIH HHS R01 DK053189
6 · The paper itself

Abstract

Obesity is associated with elevated levels of free fatty acids (FAs) and proinflammatory CD11c

Indexed as

AnimalsCD11c AntigenFatty Acid-Binding ProteinsFatty AcidsInflammationMacrophagesMiceMice, Inbred C57BLMice, ObeseMonocytesObesityStearic AcidsUp-RegulationCD11c AntigenFatty Acid-Binding ProteinsFatty Acidsstearic acidStearic Acids

Identifiers

PMID29626089
PMCPMC5940522
OpenAlexW2795739855

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.