Evidence map›Paper›PMID 29626087›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Human IgG Increases Virulence of

David Ermert, Antonin Weckel, Michal Magda, Matthias Mörgelin, Jutamas Shaughnessy, Peter A Rice, Lars Björck, Sanjay Ram, Anna M Blom

Abstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Interplay between group AMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  3. Article
  4. Article
  5. Diverse Functions of C4b-Binding Protein in Health and Disease.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

David ErmertDivision of Medical Protein Chemistry, Department of Translational Medicine, Lund University, 214 28 Malmo, Sweden; David.Ermert@med.lu.se.ORCID 0000-0003-4600-9070
Antonin WeckelDivision of Medical Protein Chemistry, Department of Translational Medicine, Lund University, 214 28 Malmo, Sweden.ORCID 0000-0002-5085-0551
Michal MagdaDivision of Medical Protein Chemistry, Department of Translational Medicine, Lund University, 214 28 Malmo, Sweden.ORCID 0000-0003-4857-0769
Matthias MörgelinDivision of Infection Medicine, Department of Clinical Sciences, Lund University, 221 84 Lund, Sweden.
Jutamas ShaughnessyDivision of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605; and.ORCID 0000-0003-0832-9954
Peter A RiceDivision of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605; and.
Lars BjörckDivision of Infection Medicine, Department of Clinical Sciences, Lund University, 221 84 Lund, Sweden.
Sanjay RamDivision of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605; and.
Anna M BlomDivision of Medical Protein Chemistry, Department of Translational Medicine, Lund University, 214 28 Malmo, Sweden.ORCID 0000-0002-1348-1734
Lund University · SEUniversity of Massachusetts Chan Medical School · US

Funding

Novel immunotherapeutics against multidrug-resistant Neisseria gonorrhoeaR01AI132296 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI RAM, SANJAY, RICE, PETER A. · 2017 to 2021
$5.5M
Immune defenses against Neisseria gonorrhoeaeR01AI114790 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI RAM, SANJAY, RICE, PETER A. · 2015 to 2019
$3.1M
Novel immunotherapeutics against multi-drug resistant Neisseria gonorrhoeaeR21AI111728 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI RAM, SANJAY, SHAUGHNESSY, JUTAMAS · 2014 to 2015
$460k
NIAID NIH HHS R01 AI114790NIAID NIH HHS R01 AI132296NIAID NIH HHS R21 AI111728
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntigens, BacterialBacterial Outer Membrane ProteinsCarrier ProteinsComplement C4b-Binding ProteinComplement Inactivating AgentsComplement System ProteinsFemaleHumansImmunoglobulin GMaleMiceMice, Inbred BALB CPhagocytosisProtein BindingStreptococcal InfectionsAntigens, BacterialBacterial Outer Membrane ProteinsCarrier ProteinsComplement C4b-Binding ProteinComplement Inactivating AgentsComplement System ProteinsImmunoglobulin GVirulence Factors

Identifiers

PMID29626087
PMCPMC6028238
OpenAlexW2796172563

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.