Evidence map›Paper›PMID 29626059›Full record

ArticleEndocrine connections2018

Evaluation of lipid profile and its relationship with blood pressure in patients with Cushing's disease.

Lang Qin, Xiaoming Zhu, Xiaoxia Liu, Meifang Zeng, Ran Tao, Yan Zhuang, Yiting Zhou, Zhaoyun Zhang, Yehong Yang, Yiming Li and 2 more

Open access · goldAbstract read
In one paragraph

Article in Endocrine connections, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Lang QinDivision of Endocrinology and MetabolismHuashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Xiaoming ZhuDivision of Endocrinology and MetabolismHuashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Xiaoxia LiuDivision of Endocrinology and MetabolismHuashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Meifang ZengDivision of Endocrinology and MetabolismHuashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Ran TaoDivision of Endocrinology and MetabolismHuashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Yan ZhuangDivision of Endocrinology and MetabolismHuashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Yiting ZhouDivision of Endocrinology and MetabolismHuashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Zhaoyun ZhangDivision of Endocrinology and MetabolismHuashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Yehong YangDivision of Endocrinology and MetabolismHuashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Yiming LiDivision of Endocrinology and MetabolismHuashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Yongfei WangDivision of NeurosurgeryHuashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China eamns@hotmail.com yehongying@huashan.org.cn.
Hongying YeDivision of Endocrinology and MetabolismHuashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China eamns@hotmail.com yehongying@huashan.org.cn.
Huashan Hospital · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe purpose of the study was to describe lipid profile and explore pathogenetic role of LDL-c on hypertension in patients with Cushing's disease (CD). Hypertension is a common feature in patients with CD. Previous study found low-density lipoprotein cholesterol (LDL-c) uptake in vascular cells might be involved in vascular remodeling in patients with CD. Therefore, we evaluated the relationship between lipid profile and the blood pressure in patients with CD.

methodsThis retrospective study included 84 patients referred to Huashan Hospital for the evaluation and diagnosis of CD from January 2012 to December 2013. All subjects had detailed clinical evaluation by the same group of endocrinology specialists to avoid subjective influences.

resultsWe found that high LDL-c patients had significant higher body mass index (BMI), systolic blood pressure (SBP), cholesterol (CHO), triglyceride (TG), and apolipoproteinB (apoB) (

conclusionsAn independent association between LDL-c and SBP was found in patients with CD. We speculate that LDL-c may be a pathogenic factor for hypertension in those patients.

Indexed as

adrenalblood pressureCDlipid profilemetabolism

Identifiers

PMID29626059
PMCPMC5931227
OpenAlexW2795868656

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.