Evidence map›Paper›PMID 29626011›Full record

ArticleThe Journal of cell biology2018

Centromere transcription allows CENP-A to transit from chromatin association to stable incorporation.

Georg O M Bobkov, Nick Gilbert, Patrick Heun

Open access · hybridAbstract read
In one paragraph

Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
25.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 132 citations in OpenAlex.

  1. Review
  2. Satellite DNAs in Drosophila koepferae (repleta group) reveal patterns of origin, chromosomal organization, transcription, and turnover in the buzzatii cluster.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026
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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Georg O M BobkovWellcome Trust Centre for Cell Biology and Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, Scotland, UK.ORCID 0000-0003-2953-9256
Nick GilbertMedical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, Scotland, UK.ORCID 0000-0003-0505-6081
Patrick HeunWellcome Trust Centre for Cell Biology and Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, Scotland, UK patrick.heun@ed.ac.uk.ORCID 0000-0001-8400-1892
Institute of Genetics and Cancer · GBUniversity of Freiburg · DEWellcome Centre for Cell Biology · GB

Funding

Medical Research Council MR/J00913X/1Wellcome Trust 092076Wellcome Trust 103897/Z/14/ZWellcome Trust 203149
6 · The paper itself

Abstract

Centromeres are essential for chromosome segregation and are specified epigenetically by the presence of the histone H3 variant CENP-A. In flies and humans, replenishment of the centromeric mark is uncoupled from DNA replication and requires the removal of H3 "placeholder" nucleosomes. Although transcription at centromeres has been previously linked to the loading of new CENP-A, the underlying molecular mechanism remains poorly understood. Here, we used

Indexed as

Transcription, GeneticAnimalsCentromereCentromere Protein AChromatinDrosophila melanogasterDrosophila ProteinsG1 PhaseInterphaseMitosisModels, BiologicalProtein StabilityRNA, MessengerRNA Polymerase IICal1 protein, DrosophilaCentromere Protein AChromatinCid protein, DrosophilaDrosophila ProteinsRNA, MessengerRNA Polymerase II

Identifiers

PMID29626011
PMCPMC5987708
OpenAlexW2796346486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.