Evidence map›Paper›PMID 29625990›Full record

ArticleApplied and environmental microbiology2018

VqsA, a Novel LysR-Type Transcriptional Regulator, Coordinates Quorum Sensing (QS) and Is Controlled by QS To Regulate Virulence in the Pathogen Vibrio alginolyticus.

Xiating Gao, Xuetong Wang, Qiaoqiao Mao, Rongjing Xu, Xiaohui Zhou, Yue Ma, Qin Liu, Yuanxing Zhang, Qiyao Wang

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Potential dsRNAs can be delivered to aquatic for defense pathogens.Frontiers in bioengineering and biotechnology · 2022
    Review
  11. Review
  12. Collective behavior and virulence arsenal of the fish pathogenFrontiers in cellular and infection microbiology · 2022
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Mechanisms underlying the virulence regulation of newEmerging microbes & infections · 2019
    Article
  18. Discovery ofInternational journal of molecular sciences · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Xiating GaoState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Xuetong WangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Qiaoqiao MaoState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Rongjing XuYantai Tianyuan Aquatic Co. Ltd., Shandong, Yantai, China.
Xiaohui ZhouDepartment of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut, USA.
Yue MaState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Qin LiuState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Yuanxing ZhangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Qiyao WangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China oaiwqiyao@ecust.edu.cn.
East China University of Science and Technology · CNUniversity of Connecticut · USYantai University · CN

Funding

Mechanisms and significance of intestinal cell proliferation in Vibrio parahaemolyticus infectionR01AI118943 · NIAID · UNIVERSITY OF CONNECTICUT STORRS · PI GEARY, STEVEN J · 2016 to 2019
$1.5M
NIAID NIH HHS R01 AI118943
6 · The paper itself

Abstract

The quorum sensing (QS) system controls bacterial group behaviors in response to cell density. In vibrios, LuxR and AphA are two master QS regulators (MQSRs) controlling gene expression in response to high or low cell density. Other regulators involved in the regulation of these two MQSRs and QS pathways remain to be determined. Here, we performed bacterial one-hybrid (B1H)-assay-based screens of transcriptional factors (TFs) to identify TFs that can directly regulate the expression of

Indexed as

Gene Expression Regulation, BacterialBacterial ProteinsBinding SitesPromoter Regions, GeneticQuorum SensingRepressor ProteinsTrans-ActivatorsTranscription FactorsVibrio alginolyticusVirulenceBacterial ProteinsLysR protein, BacteriaRepressor ProteinsTrans-ActivatorsTranscription FactorsAphAbacterial one-hybrid assayLuxRMQSRquorum sensingVibrio alginolyticusvirulenceVqsA

Identifiers

PMID29625990
PMCPMC5981076
OpenAlexW2798120661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.