Evidence map›Paper›PMID 29625986›Full record

ArticleApplied and environmental microbiology2018

Survival of the Enveloped Virus Phi6 in Droplets as a Function of Relative Humidity, Absolute Humidity, and Temperature.

Aaron J Prussin, David Otto Schwake, Kaisen Lin, Daniel L Gallagher, Lauren Buttling, Linsey C Marr

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 2 pooled it
20.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 2 syntheses or guidelines pooled it, 216 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. School district-wide renovations, indoor environmental quality, and illness absence.Journal of exposure science & environmental epidemiology · 2026
    Article
  5. Organic components modulate the morphology of respirable aerovirology-relevant aerosols.Aerosol science and technology : the journal of the American Association for Aerosol Research · 2026
    Article
  6. Inactivation of airborne pathogen surrogates by triethylene glycol.Applied and environmental microbiology · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Dependence on relative humidity in the formation of reactive oxygen species in water droplets.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Article
  20. Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Aaron J PrussinVia Department of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA aprussin@vt.edu.ORCID 0000-0002-9991-8537
David Otto SchwakeVia Department of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Kaisen LinVia Department of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Daniel L GallagherVia Department of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Lauren ButtlingVia Department of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Linsey C MarrVia Department of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.ORCID 0000-0003-3628-6891
Virginia Tech · US

Funding

The Role of Pathogen-Environment Interactions in the Pandemic Potential of InfluenzaDP2AI112243 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MARR, LINSEY · 2013 to 2016
$2.4M
NIAID NIH HHS DP2 AI112243
6 · The paper itself

Abstract

Infectious diseases caused by enveloped viruses, such as influenza, severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS), cause thousands of deaths and billions of dollars of economic losses per year. Studies have found a relationship among temperature, humidity, and influenza virus incidence, transmission, or survival; however, there are contradictory claims about whether absolute humidity (AH) or relative humidity (RH) is most important in mediating virus infectivity. Using the enveloped bacteriophage Phi6, which has been suggested as a surrogate for influenza viruses and coronaviruses, we designed a study to discern whether AH, RH, or temperature is a better predictor of virus survival in droplets. Our results show that Phi6 survived best at high (>85%) and low (<60%) RHs, with a significant decrease in infectivity at mid-range RHs (∼60 to 85%). At an AH of less than 22 g · m

Indexed as

HumidityTemperatureVirus InactivationVirus Physiological PhenomenaBacteriophagesLipid DropletscoronavirushumidityinfluenzaMERSSARS

Identifiers

PMID29625986
PMCPMC5981065
OpenAlexW2795714077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.