Evidence map›Paper›PMID 29625844›Full record

ReviewMolecular immunology2018

WHO/IUIS Allergen Nomenclature: Providing a common language.

Anna Pomés, Janet M Davies, Gabriele Gadermaier, Christiane Hilger, Thomas Holzhauser, Jonas Lidholm, Andreas L Lopata, Geoffrey A Mueller, Andreas Nandy, Christian Radauer and 11 more

Abstract readReview
In one paragraph

Review in Molecular immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. FAD: a comprehensive database merging information about food allergens.Database : the journal of biological databases and curation · 2026
    Article
  7. Calcium-binding proteins as allergens.Frontiers in allergy · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Exploring geographical variances in component-resolved diagnosis within the Asia-Pacific region.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Review
  16. Effects of Heat Treatment on Physicochemical Properties ofInternational journal of molecular sciences · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Comparative studies of seafood and reptile α- and β-parvalbumins.Protein science : a publication of the Protein Society · 2024
    Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Anna PomésIndoor Biotechnologies, Basic Research, Charlottesville, VA, USA.
Janet M DaviesSchool of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia.
Gabriele GadermaierUniversity of Salzburg, Dept. of Molecular Biology, Salzburg, Austria.
Christiane HilgerLuxembourg Institute of Health, Dept. of Infection and Immunity, Luxembourg, Luxembourg.
Thomas HolzhauserPaul-Ehrlich-Institute, Division of Allergology, Langen, Germany.
Jonas LidholmThermo Fisher Scientific, Uppsala, Sweden.
Andreas L LopataJames Cook University, Molecular Allergy Research Laboratory, Townsville, Queensland, Australia.
Geoffrey A MuellerNational Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Andreas NandyALLERGOPHARMA GmbH & Co. KG, Reinbek, Germany.
Christian RadauerMedical University of Vienna, Dept. of Pathophysiology and Allergy Research, Vienna, Austria.
Sanny K ChanNational Jewish Health, Dept. of Pediatrics, Div. of Allergy, Denver, CO, USA.
Uta JappeDivision of Clinical and Molecular Allergology, ARCN, DZL, Research Center Borstel, Borstel, Germany.
Jörg Kleine-TebbeAllergy & Asthma Center Westend, Outpatient Clinic & Clinical Research Center, Berlin, Germany.
Wayne R ThomasTelethon Kids Institute, University of Western Australia, WA, Australia.
Martin D ChapmanIndoor Biotechnologies, Basic Research, Charlottesville, VA, USA.
Marianne van HageKarolinska Institute, Department of Medicine Solna, Immunology and Allergy Unit, Karolinska University Hospital, Stockholm, Sweden.
Ronald van ReeAcademic Medical Center, Deptartments of Experimental Immunology and Otorhinolaryngology, Amsterdam, The Netherlands.
Stefan ViethsPaul-Ehrlich-Institute, Langen, Germany.
Monika RaulfInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum, Bochum, Germany.
Richard E GoodmanFood Allergy Research and Resource Program, University of Nebraska-Lincoln, Lincoln, NE, USA. Electronic address: rgoodman2@unl.edu.
WHO IUIS Allergen Nomenclature Sub-Committee

Funding

Structural and Functional Characterization of AllergensZIAES102906 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI MUELLER, GEOFFREY · 2010 to 2025
$10.0M
Intramural NIH HHS Z99 ES999999Intramural NIH HHS ZIA ES102906
6 · The paper itself

Abstract

A systematic nomenclature for allergens originated in the early 1980s, when few protein allergens had been described. A group of scientists led by Dr. David G. Marsh developed a nomenclature based on the Linnaean taxonomy, and further established the World Health Organization/International Union of Immunological Societies (WHO/IUIS) Allergen Nomenclature Sub-Committee in 1986. Its stated aim was to standardize the names given to the antigens (allergens) that caused IgE-mediated allergies in humans. The Sub-Committee first published a revised list of allergen names in 1986, which continued to grow with rare publications until 1994. Between 1994 and 2007 the database was a text table online, then converted to a more readily updated website. The allergen list became the Allergen Nomenclature database (www.allergen.org), which currently includes approximately 880 proteins from a wide variety of sources. The Sub-Committee includes experts on clinical and molecular allergology. They review submissions of allergen candidates, using evidence-based criteria developed by the Sub-Committee. The review process assesses the biochemical analysis and the proof of allergenicity submitted, and aims to assign allergen names prior to publication. The Sub-Committee maintains and revises the database, and addresses continuous challenges as new "omics" technologies provide increasing data about potential new allergens. Most journals publishing information on new allergens require an official allergen name, which involves submission of confidential data to the WHO/IUIS Allergen Nomenclature Sub-Committee, sufficient to demonstrate binding of IgE from allergic subjects to the purified protein.

Indexed as

AllergensAnimalsDatabases, FactualHumansImmunoglobulin EWorld Health OrganizationAllergensImmunoglobulin EAllergen databaseIgEIsoallergenTaxonomic nameWHO/IUIS Allergen Nomenclature

Identifiers

PMID29625844
PMCPMC6019191

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.