Evidence map›Paper›PMID 29625610›Full record

ArticleJournal of neuroinflammation2018

A novel interaction between CX

Karli Montague, Raffaele Simeoli, Joao Valente, Marzia Malcangio

Open access · goldAbstract read
In one paragraph

Article in Journal of neuroinflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Emerging role of macrophages in neuropathic pain.Journal of orthopaedic translation · 2025
    Review
  6. Article
  7. Article
  8. Innate immunity in chemotherapy-induced peripheral neuropathy: recent advances.Frontiers in pain research (Lausanne, Switzerland) · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Inflammation and Infection in Pain and the Role of GPR37.International journal of molecular sciences · 2022
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Karli MontagueWolfson Centre for Age-Related Diseases, King's College London, Guy's Campus, London, SE1 1UL, UK. karli.montague@kcl.ac.uk.ORCID http://orcid.org/0000-0001-6614-9068
Raffaele SimeoliWolfson Centre for Age-Related Diseases, King's College London, Guy's Campus, London, SE1 1UL, UK.
Joao ValenteVascular Biology and Inflammation Section, Cardiovascular School of Medicine & Science, British Heart Foundation Centre of Excellence, King's College London, Franklin-Wilkins Building, 150 Stamford Street, King's College London, London, SE1 9NH, UK.
Marzia MalcangioWolfson Centre for Age-Related Diseases, King's College London, Guy's Campus, London, SE1 1UL, UK. marzia.malcangio@kcl.ac.uk.
King's College London · GB

Funding

Medical Research Council MR/M023893/1MRF_ MR/M023893/1
6 · The paper itself

Abstract

backgroundA dose-limiting side effect of chemotherapeutic agents such as vincristine (VCR) is neuropathic pain, which is poorly managed at present. Chemokine-mediated immune cell/neuron communication in preclinical VCR-induced pain forms an intriguing basis for the development of analgesics. In a murine VCR model, CX

methodsMechanically evoked hypersensitivity was assessed in VCR-treated CCR

resultsWe show that CCR

conclusionsOur data suggests that CCL

Indexed as

AnimalsAntineoplastic Agents, PhytogenicBenzoxazinesCalcium-Binding ProteinsCell Line, TransformedDisease Models, AnimalFemaleGene Expression RegulationHyperalgesiaMaleMAP Kinase Signaling SystemMiceMice, Inbred C57BLMice, TransgenicMicrofilament ProteinsMonocytesAif1 protein, mouseAntineoplastic Agents, PhytogenicBenzoxazinesCalcium-Binding ProteinsCcr2 protein, mouseCxcr3 protein, mouseMicrofilament ProteinsPiperidinesReceptors, CCR2Receptors, CXCR3RS 102895VincristineCCL2CCR2CIPNCX3CR1MacrophageMonocyteProinflammatory cytokineSciatic nerveTHP-1Vincristine

Identifiers

PMID29625610
PMCPMC5889528
OpenAlexW2800198187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.