ReviewSeminars in dialysis2018
Hemodialysis-induced cardiovascular disease.
Review in Seminars in dialysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07459348 (Can Changes in Dialysate Sodium Concentration Improve Blood Pressure and Endothelial Function in Patients Undergoing Chronic Hemodialysis?), which is not on this map. Cited by 101 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can Changes in Dialysate Sodium Concentration Improve Blood Pressure and Endothelial Function in Patients Undergoing Chronic Hemodialysis?
Who cites it
101 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The optimal exercise modality and intensity for hemodialysis patients incorporating Bayesian network meta-analysis and systematic review.Frontiers in physiology · 2022Pooled it
- Hemodialysis-induced QRS-T spatial angle dynamics: a methodological and clinical appraisal.International urology and nephrology · 2026Article
- Hemodialysis-induced variability of the QRS-T spatial angle reveals distinct electrophysiological patterns in patients with end-stage renal disease.International urology and nephrology · 2026Article
- Revolutionizing Renal Replacement: Current Advancements in Development and Transplantation of Bioengineered Kidneys.International journal of molecular sciences · 2026Review
- Mitral valve calcific embolization leading to myocardial infarction in a patient with end-stage renal disease.Oxford medical case reports · 2026Article
- Interdialytic weight gain, carotid intima media thickness, and cardiovascular profile in children undergoing chronic hemodialysis: a multicenter study.BMC nephrology · 2026Article
- Prevalence and risk factors of pulmonary hypertension in maintenance hemodialysis patients based on echocardiography.Medicine · 2026Article
- Correlation between life satisfaction, pleasure level, and negative emotion in patients with chronic renal failure.World journal of psychiatry · 2026Article
- Serum YB-1 links dyslipidemia to NET-mediated vascular calcification in hemodialysis.Lipids in health and disease · 2026Article
- Prevalence and clinical correlates of peripheral artery disease in patients undergoing hemodialysis: a cross-sectional study from Palestine.BMC nephrology · 2026Article
- Development and preliminary psychometric evaluation of the hemodialysis patient care dependency scale (HD-CDS).PloS one · 2026Article
- Serum Phenylacetylglutamine Is a Potential Risk Factor for Aortic Stiffness in Patients with Chronic Hemodialysis.Diagnostics (Basel, Switzerland) · 2025Article
- Vascular Calcification in Chronic Kidney Disease and Hemodialysis: Pathophysiological Mechanisms and Emerging Biomarkers.Medicina (Kaunas, Lithuania) · 2025Review
- Perioperative and mid-term prognosis in coronary artery bypass grafting patients with mild renal dysfunction.Renal failure · 2025Article
- Different patterns of brain iron deposition exist in peritoneal dialysis and hemodialysis patients with cognitive impairment.Renal failure · 2025Article
- Lymphocyte Phenotypes and Protein-Bound Uremic Toxins as Determinants of Clinical Outcomes in Hemodialysis Patients.International journal of molecular sciences · 2025Observational
- Cardiovascular Biomarkers in Nocturnal Hemodialysis and Their Association With Physical Performance.Hemodialysis international. International Symposium on Home Hemodialysis · 2025Article
- Article
- Cardiac Indices Parameters on the Ultrasonic Cardiac Output Monitor as Potential Indicators to Predict the Ultrafiltration Endpoint Success in Acute Heart Failure Treatment.Reviews in cardiovascular medicine · 2025Article
- Predicting 3-year all-cause mortality in patients undergoing hemodialysis using machine learning.Journal of nephrology · 2025Article
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
More than half of all deaths among end stage renal disease (ESRD) patients are due to cardiovascular disease (CVD). Cardiovascular changes secondary to renal dysfunction, including fluid overload, uremic cardiomyopathy, secondary hyperparathyroidism, anemia, altered lipid metabolism, and accumulation of gut microbiota-derived uremic toxins like trimethylamine N-oxidase, contribute to the high risk for CVD in the ESRD population. In addition, conventional hemodialysis (HD) itself poses myocardial stress and injury on the already compromised cardiovascular system in uremic patients. This review will provide an overview of cardiovascular changes in chronic kidney disease and ESRD, a description of reported mechanisms for HD-induced myocardial injury, comparison of HD with other treatment modalities in the context of CVD, and possible management strategies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.