Evidence map›Paper›PMID 29624599›Full record

ArticlePloS one2018

A snapshot of gut microbiota of an adult urban population from Western region of India.

Disha Tandon, Mohammed Monzoorul Haque, Saravanan R, Shafiq Shaikh, Sriram P, Ashok Kumar Dubey, Sharmila S Mande

Abstract readComparative Study
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

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  9. Human intestinal microbiome: Role in health and disease.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Disha TandonBio-Sciences R&D Division, TCS Research, Tata Consultancy Services Ltd., Hadapsar Industrial Estate, Pune Maharashtra, India.
Mohammed Monzoorul HaqueBio-Sciences R&D Division, TCS Research, Tata Consultancy Services Ltd., Hadapsar Industrial Estate, Pune Maharashtra, India.
Saravanan RTata Chemicals Ltd. Innovation Centre, Ambedveth, Mulshi, Pune, Maharashtra, India.
Shafiq ShaikhVeeda Clinical Research Pvt. Ltd. Near IIM, Ambawadi, Ahmedabad, Gujarat, India.
Sriram PGenotypic Technology (P) Ltd., Poojari Layout, Bangalore, India.
Ashok Kumar DubeyTata Chemicals Ltd. Innovation Centre, Ambedveth, Mulshi, Pune, Maharashtra, India.ORCID 0000-0002-1916-6655
Sharmila S MandeBio-Sciences R&D Division, TCS Research, Tata Consultancy Services Ltd., Hadapsar Industrial Estate, Pune Maharashtra, India.ORCID 0000-0002-2614-1982

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human gut microbiome contributes to a broad range of biochemical and metabolic functions that directly or indirectly affect human physiology. Several recent studies have indicated that factors like age, geographical location, genetic makeup, and individual health status significantly influence the diversity, stability, and resilience of the gut microbiome. Of the mentioned factors, geographical location (and related dietary/socio-economic context) appears to explain a significant portion of microbiome variation observed in various previously conducted base-line studies on human gut microbiome. Given this context, we have undertaken a microbiome study with the objective of cataloguing the taxonomic diversity of gut microbiomes sampled from an urban cohort from Ahmedabad city in Western India. Computational analysis of microbiome sequence data corresponding to 160 stool samples (collected from 80 healthy individuals at two time-points, 60 days apart) has indicated a Prevotella-dominated microbial community. Given that the typical diet of participants included carbohydrate and fibre-rich components (predominantly whole grains and legume-based preparations), results appear to validate the proposed correlation between diet/geography and microbiome composition. Comparative analysis of obtained gut microbiome profiles with previously published microbiome profiles from US, China, Finland, and Japan additionally reveals a distinct taxonomic and (inferred) functional niche for the sampled microbiomes.

Indexed as

Gastrointestinal MicrobiomeActinobacteriaAdultBacillotaBacteroidetesCohort StudiesDietFemaleFinlandHumansIndiaJapanMaleMicrobial ConsortiaPhylogeographyPrevotella

Identifiers

PMID29624599
PMCPMC5889170

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.