ArticlePediatric research2018
Maternal body mass index and risk of intraventricular hemorrhage in preterm infants.
Article in Pediatric research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- The impact of pre-pregnancy body mass index and maternal diseases on the offspring outcomes in preterm infants < 32 weeks: five-year retrospective mediation analysis.BMC pregnancy and childbirth · 2026Article
- Impact of maternal prepregnancy body mass index on neonatal outcomes following extremely preterm birth.Obesity (Silver Spring, Md.) · 2025Article
- The association of maternal overweight on long-term neurodevelopmental outcomes in premature infants (< 29 weeks) at 18-24 months corrected age.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Linked birth cohort files for perinatal health research: California as a model for methodology and implementation.Annals of epidemiology · 2023Article
- Critical examination of relationships between early growth and childhood overweight in extremely preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- In-hospital mortality and morbidity among extremely preterm infants in relation to maternal body mass index.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BackgroundIntraventricular hemorrhage (IVH) and pre-pregnancy obesity and underweight have been linked to inflammatory states. We hypothesize that IVH in preterm infants is associated with pre-pregnancy obesity and underweight due to an inflammatory intrauterine environment.MethodsPopulation-based study of infants born between 22 and 32 weeks' gestation from 2007 to 2011. Data were extracted from vital statistics and the California Perinatal Quality Care Collaborative. Results were examined for all cases (any IVH) and for severe IVH.ResultsAmong 20,927 infants, 4,818 (23%) had any IVH and 1,514 (7%) had severe IVH. After adjustment for confounders, there was an increased risk of IVH associated with pre-pregnancy obesity, relative risk 1.14 (95% confidence interval (CI) 1.06, 1.32) for any IVH, and 1.25 (85% CI 1.10, 1.42) for severe IVH. The direct effect of pre-pregnancy obesity on any IVH was significant (P<0.001) after controlling for antenatal inflammation-related conditions, but was not significant after controlling for gestational age (P=0.56).ConclusionPre-pregnancy obesity was found to be a risk factor for IVH in preterm infants; however, this relationship appeared to be largely mediated through the effect of BMI on gestational age at delivery. The etiology of IVH is complex and it is important to understand the contributing maternal factors.
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