Evidence map›Paper›PMID 29624523›Full record

Trial reportPsychosomatic medicine

Optimizing a Positive Psychology Intervention to Promote Health Behaviors After an Acute Coronary Syndrome: The Positive Emotions After Acute Coronary Events III (PEACE-III) Randomized Factorial Trial.

Christopher M Celano, Ariana M Albanese, Rachel A Millstein, Carol A Mastromauro, Wei-Jean Chung, Kirsti A Campbell, Sean R Legler, Elyse R Park, Brian C Healy, Linda M Collins and 2 more

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychosomatic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02754895 nacompletednot on this map

Positive Psychology for Acute Coronary Syndrome Patients: a Factorial Design Study

TypeinterventionalSponsorMassachusetts General HospitalRan2014 to 2017Enrolled128ConditionsAcute Coronary SyndromeArmsPositive Psychology (PP), Motivational Interviewing (MI)
NCT06624358 narecruitingnot on this map

Physical Activity in Adolescents With Chronic Kidney Disease

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2025 to 2028Enrolled100ConditionsChronic Kidney DiseasesArmsIncrease Physical Activity
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Effectiveness of booster strategies to promote physical activity maintenance: a systematic review and meta-analysis.The international journal of behavioral nutrition and physical activity · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Christopher M CelanoFrom the Harvard Medical School (Celano, Millstein, Chung, Campbell, Legler, Park, Healy, Januzzi, Huffman); Departments of Psychiatry (Celano, Albanese, Millstein, Mastromauro, Chung, Campbell, Legler, Park, Huffman) and Neurology (Healy), Massachusetts General Hospital, Boston; The Methodology Center and Department of Human Development and Family Studies (Collins), Pennsylvania State University, University Park; and Division of Cardiology (Januzzi), Department of Medicine, Massachusetts General Hospital and Cardiometabolic Trials, Baim Institute for Clinical Research, Boston.
Ariana M Albanese
Rachel A Millstein
Carol A Mastromauro
Wei-Jean Chung
Kirsti A Campbell
Sean R Legler
Elyse R Park
Brian C Healy
Linda M Collins
James L Januzzi
Jeff C Huffman

Funding

Developing a positive psychology intervention to improve cardiac health behaviorsR01HL113272 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HUFFMAN, JEFF C · 2013 to 2017
$2.6M
A positive psychology intervention to promote health behaviors in heart failureK23HL123607 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI CELANO, CHRISTOPHER M · 2015 to 2019
$859k
Testing the feasibility and preliminary efficacy of a multilevel intervention to promote physical activity among patients with metabolic syndromeK23HL135277 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MILLSTEIN, RACHEL A. · 2017 to 2021
$834k
NHLBI NIH HHS K23 HL123607NHLBI NIH HHS K23 HL135277NHLBI NIH HHS R01 HL113272
6 · The paper itself

Abstract

objectiveDespite the clear benefits of physical activity and related behaviors on prognosis, most patients experiencing an acute coronary syndrome (ACS) remain nonadherent to these behaviors. Deficits in positive psychological constructs (e.g., optimism) are linked to reduced participation in health behaviors, supporting the potential utility of a positive psychology (PP)-based intervention in post-ACS patients. Accordingly, we aimed to identify optimal components of a PP-based intervention to promote post-ACS physical activity.

methodsAs part of a multiphase optimization strategy, we completed a randomized factorial trial with eight conditions in 128 post-ACS patients to efficiently identify best-performing intervention components. All participants received a PP-based intervention, with conditions varying in duration (presence/absence of booster sessions), intensity (weekly/daily PP exercises), and content (PP alone or combined with motivational interviewing), allowing three concurrent comparisons within the trial. The study aims included assessments of the overall feasibility, acceptability, and impact of the intervention, along with the primary aim of determining which components were associated with objectively measured physical activity and self-reported health behavior adherence at 16 weeks, assessed using longitudinal models.

resultsThe intervention was well accepted and associated with substantial improvements in behavioral and psychological outcomes. Booster sessions were associated with greater activity to a nearly significant degree (β = 8.58, 95% confidence interval = -0.49-17.65, effect size difference = .43, p = .064), motivational interviewing was associated with overall adherence (β = 0.95, 95% confidence interval = 0.02-1.87, effect size difference = .39, p = .044), and weekly exercise completion was generally superior to daily.

conclusionsThese findings will enable optimization of the PP-based intervention in preparation for a well-powered controlled trial. CLINICAL

trial registrationClinicaltrials.gov, NCT02754895.

Indexed as

Health BehaviorOutcome and Process Assessment, Health CareAcute Coronary SyndromeAgedCognitive Behavioral TherapyFemaleHealth PromotionHumansMaleMiddle Aged

Identifiers

PMID29624523
PMCPMC6023730

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.