Evidence map›Paper›PMID 29624449›Full record

ReviewAmerican journal of respiratory and critical care medicine2018

Defining Impaired Respiratory Health. A Paradigm Shift for Pulmonary Medicine.

Paul A Reyfman, George R Washko, Mark T Dransfield, Avrum Spira, MeiLan K Han, Ravi Kalhan

Abstract readReview
In one paragraph

Review in American journal of respiratory and critical care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Investigating human lung resilience, its evolutionary history and its relation to COPD.American journal of physiology. Lung cellular and molecular physiology · 2026
    Review
  5. Progenitor Resilience and the Early Onset of Chronic Lung Diseases: NHLBI workshop report.American journal of respiratory cell and molecular biology · 2026
    Article
  6. Article
  7. Article
  8. Proteomic Risk Score of Increased Respiratory Susceptibility: A Multicohort Study.American journal of respiratory and critical care medicine · 2025
    Article
  9. Article
  10. Article
  11. Efficacy and safety ofFrontiers in pharmacology · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. LKB1 deficiency upregulates RELM-α to drive airway goblet cell metaplasia.Cellular and molecular life sciences : CMLS · 2021
    Article
  16. Defining Resilience: A Critical Step to Promote Respiratory Health.Annals of the American Thoracic Society · 2021
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paul A Reyfman1 Asthma and COPD Program, Division of Pulmonary and Critical Care Medicine, and.ORCID 0000-0002-6435-6001
George R Washko2 Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Mark T Dransfield3 Lung Health Center, University of Alabama at Birmingham, Birmingham, Alabama.
Avrum Spira4 BU-BMC Cancer Center and Division of Computational Biomedicine, Boston University School of Medicine, Boston, Massachusetts; and.
MeiLan K Han5 Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
Ravi Kalhan1 Asthma and COPD Program, Division of Pulmonary and Critical Care Medicine, and.ORCID 0000-0003-2443-0876

Funding

Transitions from Impaired Respiratory Health to Lung DiseaseR01HL122477 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RAVI KALHAN · 2014 to 2026
$17.3M
UAB Mentoring Program in COPD Patient Oriented ResearchK24HL140108 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DRANSFIELD, MARK T · 2018 to 2022
$439k
A Systems Biology Approach to Mapping Aging in the lungF32HL136111 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI REYFMAN, PAUL A · 2017 to 2018
$134k
NHLBI NIH HHS F32 HL136111NHLBI NIH HHS K24 HL140108NHLBI NIH HHS R01 HL122477
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansLungLung DiseasesPulmonary Medicine

Identifiers

PMID29624449
PMCPMC6118019

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.