Evidence map›Paper›PMID 29624412›Full record

ArticleChildhood obesity (Print)2018

Prenatal Development and Adolescent Obesity: Two Distinct Pathways to Diabetes in Adulthood.

Janne Boone-Heinonen, Rebecca M Sacks, Erin E Takemoto, Elizabeth R Hooker, Nathan F Dieckmann, Curtis S Harrod, Kent L Thornburg

Abstract read
In one paragraph

Article in Childhood obesity (Print), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Janne Boone-Heinonen1 Oregon Health & Science University-Portland State University, School of Public Health , Portland, OR.
Rebecca M Sacks1 Oregon Health & Science University-Portland State University, School of Public Health , Portland, OR.
Erin E Takemoto1 Oregon Health & Science University-Portland State University, School of Public Health , Portland, OR.
Elizabeth R Hooker1 Oregon Health & Science University-Portland State University, School of Public Health , Portland, OR.
Nathan F Dieckmann2 Oregon Health & Science University, School of Nursing and School of Medicine , Portland, OR.
Curtis S Harrod1 Oregon Health & Science University-Portland State University, School of Public Health , Portland, OR.
Kent L Thornburg4 Bob and Charlee Moore Institute for Nutrition and Wellness, Oregon Health & Science University , Portland, OR.
Oregon Health & Science University · USPortland State University · US

Funding

Scholars in Women's Health Research Across the LifespanK12HD043488 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI MYATT, LESLIE · 2002 to 2023
$10.4M
The dynamics of transgenerational obesity: simulating systems solutionsK01DK102857 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI BOONE-HEINONEN, JANNE · 2015 to 2017
$433k
NICHD NIH HHS K12 HD043488NIDDK NIH HHS K01 DK102857
6 · The paper itself

Abstract

objectiveHigher body-mass index (BMI) and lower birth weight (BW) are associated with elevated risk of diabetes in adulthood, but the extent to which they compose two distinct pathways is unclear.

methodsWe used data from the National Longitudinal Study of Adolescent to Adult Health, a cohort of adolescents (1994-1995) followed for 14 years over four waves into adulthood (n = 13,413). Sex-stratified path analysis was used to examine pathways from BW [kg; linear (BW) and quadratic (BW

resultsTwo pathways from BW to pre/diabetes were characterized: one from higher BW to elevated BMI and pre/diabetes and a second from lower BW, independent of BMI. In the BMI-independent pathway, greater BW was associated with marginally lower odds of pre/diabetes in women, but not men. Girls born at lower and higher BW exhibited elevated BMI in adolescence [coeff (95% CI): BW: -2.1 (-4.1, -0.05); BW

conclusionsFindings suggest that in girls, slowing BMI gain is critical for diabetes prevention, yet it may not address distinct pathology stemming from early life.

Indexed as

Infant, Low Birth WeightAdolescentAdolescent HealthAdultBirth WeightBody Mass IndexDiabetes MellitusFemaleFetal DevelopmentHumansLongitudinal StudiesMalePediatric ObesityPrediabetic StatePregnancyRisk Factorsadolescentsbirth weightbody mass indexdevelopmental originsobesity

Identifiers

PMID29624412
PMCPMC5910034
OpenAlexW2796289448

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.