Evidence map›Paper›PMID 29624188›Full record

SynthesisJournal of hospital medicine2018

Safe Opioid Prescribing for Acute Noncancer Pain in Hospitalized Adults: A Systematic Review of Existing Guidelines.

Shoshana J Herzig, Susan L Calcaterra, Hilary J Mosher, Matthew V Ronan, Nicole Van Groningen, Lili Shek, Anthony Loffredo, Michelle Keller, Anupam B Jena, Teryl K Nuckols

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Journal of hospital medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  5. Review
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  11. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Shoshana J HerzigDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA. sherzig@bidmc.harvard.edu.
Susan L CalcaterraDepartment of Medicine, Denver Health Medical Center, Denver, Colorado, USA.
Hilary J MosherThe Comprehensive Access and Delivery Research and Evaluation Center at the Iowa City Veterans Affairs Healthcare System, Iowa City, Iowa, USA.
Matthew V RonanHarvard Medical School, Boston, Massachusetts, USA.
Nicole Van GroningenDivision of General Internal Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Lili ShekDivision of General Internal Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Anthony LoffredoDepartment of Emergency Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Michelle KellerDivision of Health Services Research, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Anupam B JenaHarvard Medical School, Boston, Massachusetts, USA.
Teryl K NuckolsDivision of General Internal Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Cedars-Sinai Medical Center · USHarvard University · USIowa City VA Health Care System · USMassachusetts General Hospital · USRoxbury Community College · USUniversity of Colorado Denver · US

Funding

NRSA Training CoreTL1TR001883 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ALEX BUI, Nina Thawata Harawa · 2016 to 2026
$8.6M
UCLA Clinical and Translational Science InstituteTL1TR000121 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$2.7M
Improving Use of Sedating Medications in Hospitalized Older AdultsK23AG042459 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI HERZIG, SHOSHANA J · 2013 to 2017
$783k
NCATS NIH HHS TL1 TR000121NCATS NIH HHS TL1 TR001883NIA NIH HHS K23 AG042459
6 · The paper itself

Abstract

backgroundPain is common among hospitalized patients. Inpatient prescribing of opioids is not without risk. Acute pain management guidelines could inform safe prescribing of opioids in the hospital and limit associated unintended consequences. PURPOSE: To evaluate the quality and content of existing guidelines for acute, noncancer pain management. DATA SOURCES: The National Guideline Clearinghouse, MEDLINE via PubMed, websites of relevant specialty societies and other organizations, and selected international search engines. STUDY SELECTION: Guidelines published between January 2010 and August 2017 addressing acute, noncancer pain management among adults were considered. Guidelines that focused on chronic pain, specific diseases, and the nonhospital setting were excluded. DATA EXTRACTION: Quality was assessed using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument. DATA SYNTHESIS: Four guidelines met the selection criteria. Most recommendations were based on expert consensus. The guidelines recommended restricting opioids to severe pain or pain that has not responded to nonopioid therapy, using the lowest effective dose of short-acting opioids for the shortest duration possible, and co-prescribing opioids with nonopioid analgesics. The guidelines generally recommended checking the prescription drug monitoring program when prescribing opioids, developing goals for patient recovery, and educating patients regarding the risks and side effects of opioid therapy. Additional recommendations included using an opioid dose conversion guide, avoidance of co-administration of parenteral and oral opioids, and using caution when co-prescribing opioids with other central nervous system depressants.

conclusionsGuidelines, based largely on expert opinion, recommend judicious prescribing of opioids for severe, acute pain. Future work should assess the implications of these recommendations on hospital-based pain management.

Indexed as

Practice Patterns, Physicians'Acute PainAnalgesics, OpioidGuideline AdherenceHospitalizationHumansPain ManagementAnalgesics, Opioid

Identifiers

PMID29624188
PMCPMC6278929
OpenAlexW2795723888

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.