Evidence map›Paper›PMID 29624124›Full record

ReviewTranscription2018

Architecture of the RNA polymerase II elongation complex: new insights into Spt4/5 and Elf1.

Haruhiko Ehara, Shun-Ichi Sekine

Abstract readReview
In one paragraph

Review in Transcription, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  2. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Haruhiko Eharaa RIKEN Center for Life Science Technologies , 1-7-22 Suehiro-cho, Tsurumi-ku , Yokohama 230-0045 , Japan.ORCID 0000-0002-7420-145X
Shun-Ichi Sekinea RIKEN Center for Life Science Technologies , 1-7-22 Suehiro-cho, Tsurumi-ku , Yokohama 230-0045 , Japan.ORCID 0000-0001-8174-8704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcription by RNA polymerase II (Pol II) is accomplished with the aid of numerous accessory factors specific to each transcriptional stage. The structure of the Pol II elongation complex (EC) bound with Spt4/5, Elf1, and TFIIS unveiled the sophisticated basal EC architecture essential for transcription elongation and other transcription-related events.

Indexed as

Transcription Elongation, GeneticArchaeaCell NucleusComputer SimulationCrystallography, X-RayEukaryotaMolecular ConformationMultiprotein ComplexesRNA Polymerase IITranscriptional Elongation FactorsMultiprotein ComplexesRNA Polymerase IITranscriptional Elongation Factorscryo-EMElf1elongation complexRNA polymerase IISpt4/5TFIIStranscription elongationX-ray crystallography

Identifiers

PMID29624124
PMCPMC6150629

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.