Evidence map›Paper›PMID 29623622›Full record

ArticlePharmacoEconomics - open2018

Direct Medical Costs of Type 2 Diabetes in France: An Insurance Claims Database Analysis.

Bernard Charbonnel, Dominique Simon, Jean Dallongeville, Isabelle Bureau, Sylvie Dejager, Laurie Levy-Bachelot, Julie Gourmelen, Bruno Detournay

Abstract read
In one paragraph

Article in PharmacoEconomics - open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. Costs and where to find them: identifying unit costs for health economic evaluations of diabetes in France, Germany and Italy.The European journal of health economics : HEPAC : health economics in prevention and care · 2020
    Review
  17. Persistence with Basal Insulin and Frequency of Hypoglycemia Requiring Hospitalization in Patients with Type 2 Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bernard CharbonnelHôtel Dieu Hospital, Nantes, France.
Dominique SimonDiabetes Department and ICAN (Institute of Cardiometabolism And Nutrition), Pitié Hospital, Paris, France.
Jean DallongevilleINSERM-U1167, Lille, France.
Isabelle BureauCemka-Eval, 43 Bd du Maréchal Joffre, 92 340, Bourg-la-Reine, France.
Sylvie DejagerMerck Sharpe & Dohme, Courbevoie, France.
Laurie Levy-BachelotMerck Sharpe & Dohme, Courbevoie, France.
Julie GourmelenINSERM UMS 011, Villejuif, France.
Bruno DetournayCemka-Eval, 43 Bd du Maréchal Joffre, 92 340, Bourg-la-Reine, France. Bruno.detournay@cemka.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOur objects was to estimate the direct healthcare costs of type 2 diabetes mellitus (T2DM) in France in 2013.

methodsData were drawn from a random sample of ≈600,000 patients registered in the French national health insurances database, which covers 90% of the French population. An algorithm was used to select patients with T2DM. Direct healthcare costs from a collective perspective were derived from the database and compared with those from a control group to estimate the cost of diabetes and related comorbidities. Overall direct costs were also compared according to the diabetes therapies used throughout the year 2013.

resultsCost analysis was available for a sample of 25,987 patients with T2DM (mean age 67.5 ± standard deviation 12.5; 53.9% male) matched with a control group of 76,406 individuals without diabetes. Overall per patient per year medical expenditures were €6506 ± 10,106 in the T2DM group as compared with €3668 ± 6954 in the control group. The cost difference between the two groups was €2838 per patient per year, mainly due to hospitalizations, medication and nursing care costs. Total per capita annual costs were lowest for patients receiving metformin monotherapy (€4153 ± 6170) and highest for those receiving insulin (€12,890). However, apart from patients receiving insulin, costs did not differ markedly across the different oral treatment patterns.

conclusionExtrapolating these results to the whole T2DM population in France, total direct costs of diagnosed T2DM in 2013 was estimated at over €8.5 billion. This estimate highlights the substantial economic burden of this condition on society.

Identifiers

PMID29623622
PMCPMC5972121

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.