Evidence map›Paper›PMID 29623080›Full record

ArticleFrontiers in immunology2018

Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner.

Rui Liu, Ashleigh King, Philippe Bouillet, David M Tarlinton, Andreas Strasser, Jörg Heierhorst

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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  8. E3 Ubiquitin Ligase Fbw7 Regulates the Survival of Mature B Cells.Journal of immunology (Baltimore, Md. : 1950) · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rui LiuMolecular Genetics Unit, St. Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Ashleigh KingMolecular Genetics Unit, St. Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Philippe BouilletMolecular Genetics of Cancer Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
David M TarlintonDepartment of Immunology and Pathology, Monash University, Melbourne, VIC, Australia.
Andreas StrasserMolecular Genetics of Cancer Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Jörg HeierhorstMolecular Genetics Unit, St. Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
University of Melbourne · AUSt Vincents Institute of Medical Research · AUMonash University · AU

Funding

Worldwide Cancer Research 16-0156
6 · The paper itself

Abstract

The proapoptotic BH3-only protein BIM (

Indexed as

HomeostasisAnimalsApoptosisBcl-2-Like Protein 11B-LymphocytesCell SurvivalGene DeletionGenes, mycGenotypeImmunophenotypingLymphopoiesisMicePhenotypeBcl-2-Like Protein 11apoptosisB cell lymphomaBCL-2 familyBH3-only proteinBIMB lymphocytescell death

Identifiers

PMID29623080
PMCPMC5874283
OpenAlexW2792162977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.