Evidence map›Paper›PMID 29623043›Full record

ArticleFrontiers in physiology2018

Developmental Ethanol Exposure Causes Reduced Feeding and Reveals a Critical Role for Neuropeptide F in Survival.

Amanda Guevara, Hillary Gates, Brianna Urbina, Rachael French

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amanda GuevaraBiological Sciences, San Jose State University, San Jose, CA, United States.
Hillary GatesBiological Sciences, San Jose State University, San Jose, CA, United States.
Brianna UrbinaBiological Sciences, San Jose State University, San Jose, CA, United States.
Rachael FrenchBiological Sciences, San Jose State University, San Jose, CA, United States.
San Jose State University · US

Funding

NIGMS MARC UNDERGRADUATE RESEARCH TRAINING GRANTT34GM008253 · NIGMS · SAN JOSE STATE UNIVERSITY · PI OUVERNEY, CLEBER COSTA · 1988 to 2020
$8.4M
Genetic and Molecular Mechanisms of Ethanol-Induced Developmental DefectsSC3GM103739 · NIGMS · SAN JOSE STATE UNIVERSITY · PI FRENCH, RACHAEL LOUISE · 2013 to 2016
$430k
NIGMS NIH HHS SC3 GM103739NIGMS NIH HHS T34 GM008253
6 · The paper itself

Abstract

Food intake is necessary for survival, and natural reward circuitry has evolved to help ensure that animals ingest sufficient food to maintain development, growth, and survival. Drugs of abuse, including alcohol, co-opt the natural reward circuitry in the brain, and this is a major factor in the reinforcement of drug behaviors leading to addiction. At the junction of these two aspects of reward are alterations in feeding behavior due to alcohol consumption. In particular, developmental alcohol exposure (DAE) results in a collection of physical and neurobehavioral disorders collectively referred to as Fetal Alcohol Spectrum Disorder (FASD). The deleterious effects of DAE include intellectual disabilities and other neurobehavioral changes, including altered feeding behaviors. Here we use

Indexed as

developmental ethanol exposuredevelopmental lethalityDrosophila melanogasterfeeding behaviorNeuropeptide Y

Identifiers

PMID29623043
PMCPMC5875382
OpenAlexW2793744513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.