Evidence map›Paper›PMID 29622972›Full record

ReviewThe Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology2017

Elevated troponin in patients with acute stroke - Is it a true heart attack?

George V Dous, Angela C Grigos, Richard Grodman

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Prehospital misdiagnosis of acute cerebral disease for acute coronary syndrome: a retrospective study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2022
    Article
  6. Review
  7. Patients of COVID-19 may benefit from sustained Lopinavir-combined regimen and the increase of Eosinophil may predict the outcome of COVID-19 progression.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

George V DousSUNY Downstate, Department of Cardiology, Brooklyn, New York, United States.
Angela C GrigosRichmond University Medical Center, Department of Medicine, Staten Island, New York, United States.
Richard GrodmanRichmond University Medical Center, Department of Cardiology, Staten Island, New York, United States.
Richmond University Medical Center · USSUNY Downstate Health Sciences University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the prognostic value of a positive troponin in an acute stroke patient is still uncertain, it is a commonly encountered clinical situation given that Ischemic Heart Disease (IHD) and cerebrovascular disease (CVD) frequently co-exist in the same patient and share similar risk factors. Our objectives in this review are to (1) identify the biologic relationship between acute cerebrovascular stroke and elevated troponin levels, (2) determine the pathophysiologic differences between positive troponin in the setting of acute stroke versus acute myocardial infarction (AMI), and (3) examine whether positive troponin in the setting of acute stroke has prognostic significance. We also will provide an insight analysis of some of the available studies and will provide guidance for a management approach based on the available data according to the current guidelines.

Indexed as

ACS, acute coronary syndromeAMI, acute myocardial infarctionCAD, Coronary Artery DiseaseCAST, Chinese Acute Stroke TrialCK-MB, Creatine Kinase-MBCT, computed tomographycTnI, Troponin IcTnT, Troponin TCVD, Cardiovascular DiseaseDAPT, dual antiplatelet therapyECG, electrocardiogramICH, intracranial hemorrhageIHD, Ischemic Heart DiseaseIST, International Stroke TrialLDL, low-density lipoproteinLV, left ventricularMI, myocardial infarctionMyocardial infarctionNeurogenic heart syndromeNHS, neurogenic heart syndromeSAH, subarachnoid hemorrhageStrokeTIA, Transient Ischemic AttacksTRELAS, The Troponin Elevation in Acute Ischemic StrokeTroponin

Identifiers

PMID29622972
PMCPMC5883484
OpenAlexW2588031324

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.