Evidence map›Paper›PMID 29622590›Full record

ArticleJournal of the American Heart Association2018

Carotid Atherosclerosis Detected by Ultrasonography: A National Cross-Sectional Study.

Xiaojun Wang, Wenzhen Li, Fujian Song, Longde Wang, Qian Fu, Shiyi Cao, Yong Gan, Wei Zhang, Wei Yue, Feng Yan and 6 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 119 citations in OpenAlex.

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  13. Relationship Between Carotid Artery Remodeling Characteristics and Early Carotid Atherosclerosis: An Ultrasonographic Multicenter Study.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 2 countries.

Xiaojun WangDepartment of Social Medicine and Health Management, School of Public Health, Tongji Medical College.
Wenzhen LiDepartment of Social Medicine and Health Management, School of Public Health, Tongji Medical College.
Fujian SongNorwich Medical School, Faculty of Medicine and Health Science, University of East Anglia, Norwich, United Kingdom.
Longde WangThe National Health and Family Commission, Beijing, China.
Qian FuSchool of Medicine and Health Management, Tongji Medical College.
Shiyi CaoDepartment of Social Medicine and Health Management, School of Public Health, Tongji Medical College.
Yong GanDepartment of Social Medicine and Health Management, School of Public Health, Tongji Medical College.
Wei ZhangDepartment of Medical Ultrasound, Tongji Hospital & Medical College.
Wei YueDepartment of Neurology, Tianjin Huanhu Hospital, Tianjin, China.
Feng YanDepartment of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing, China.
Wenhuan ShiDepartment of Science and Education, The Third Hospital of Shijiazhuang, Shijiazhuang, Hebei, China.
Xiaoli WangDepartment of Neurology, Harrison International Peace Hospital, Hengshui, Hebei, China.
Hong ZhangDepartment of Science and Education, People's Hospital of Deyang City, Sichuan, China.
Hao ZhangDepartment of Neurology, Rizhao People's Hospital, Rizhao, Shandong, China.
Zhihong WangDepartment of Neurosurgery, Shenzhen Second People's Hospital Shenzhen University, Shenzhen, Guangdong, China zuxunlu@yahoo.com lyyy_wzh@163.com.
Zuxun LuDepartment of Social Medicine and Health Management, School of Public Health, Tongji Medical College zuxunlu@yahoo.com lyyy_wzh@163.com.
Harrison International Peace Hospital · CNPeople’s Hospital of Rizhao · CNCapital Medical University · CNFirst Hospital of Shijiazhuang · CNNational Health and Family Planning Commission · CNShenzhen Second People's Hospital · CNTianjin Huanhu Hospital · CNTongji Hospital · CNTongji University · CNUniversity of East Anglia · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarotid atherosclerosis (CA) is a reflector of generalized atherosclerosis that is associated with systemic vascular disease. Data are limited on the epidemiology of carotid lesions in a large, nationally representative population sample. We aimed to evaluate the prevalence of CA detected by carotid ultrasonography and related risk factors based on a national survey in China. METHODS AND

resultsA total of 107 095 residents aged ≥40 years from the China National Stroke Prevention Project underwent carotid ultrasound examination. Participants with carotid endarterectomy or carotid stenting and those with stroke or coronary heart disease were excluded. Data from 84 880 participants were included in the analysis. CA was defined as increased intima-media thickness (IMT) ≥1 mm or presence of plaques. Of the 84 880 participants, 46.4% were men, and the mean age was 60.7±10.3 years. The standardized prevalence of CA was 36.2% overall, increased with age, and was higher in men than in women. Prevalence of CA was higher among participants living in rural areas than in urban areas. Approximately 26.5% of participants had increased IMT, and 13.9% presented plaques. There was an age-related increase in participants with increased IMT, plaque presence, and stenosis. In multiple logistic regression analysis, older age, male sex, residence in rural areas, smoking, alcohol consumption, physical inactivity, obesity, hypertension, diabetes mellitus, and dyslipidemia were associated with CA.

conclusionsCA was highly prevalent in a middle-aged and older Chinese population. This result shows the potential clinical importance of focusing on primary prevention of atherosclerosis progression.

Indexed as

AdultAgedAged, 80 and overAtherosclerosisCarotid ArteriesCarotid Artery DiseasesChinaCross-Sectional StudiesFemaleHumansIncidenceMaleMiddle AgedPrevalenceReproducibility of ResultsRetrospective Studiesatherosclerosiscarotid ultrasoundChinaepidemiologyrisk factor

Identifiers

PMID29622590
PMCPMC6015437
OpenAlexW2796009016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.