ArticleEnvironmental health : a global access science source2018
Longitudinal associations of long-term exposure to ultrafine particles with blood pressure and systemic inflammation in Puerto Rican adults.
Article in Environmental health : a global access science source, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Systematic review and meta-analysis on the health effects of long-term exposure to ultrafine particles.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- Air Pollution and Temperature: a Systematic Review of Ubiquitous Environmental Exposures and Sudden Cardiac Death.Current environmental health reports · 2023Pooled it
- Effects of Ambient Air Pollution on Blood Pressure Among Children and Adolescents: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2021Pooled it
- Ambient Ultrafine Particles and Hypertensive Disorders of Pregnancy: A Mediation Analysis of Homocysteine in a Birth Cohort.Environment & health (Washington, D.C.) · 2026Article
- Short-Term and Long-Term Effects of Inhaled Ultrafine Particles on Blood Markers of Cardiovascular Diseases: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Short- and Long-Term Effects of Inhaled Ultrafine Particles on Blood Pressure: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Scalable Multipollutant Exposure Assessment Using Routine Mobile Monitoring Platforms.Research report (Health Effects Institute) · 2024Article
- Review
- Exposure to ultrafine particles and cognitive decline among older people in the United States.Environmental research · 2023Article
- Relationship between traffic-related air pollution and inflammation biomarkers using structural equation modeling.The Science of the total environment · 2023Article
- Time Trends in Ischemic Heart Disease Mortality Attributable to PMInternational journal of environmental research and public health · 2023Article
- Use of candles and risk of cardiovascular and respiratory events in a Danish cohort study.Indoor air · 2022Article
- Solar Activity Is Associated With Diastolic and Systolic Blood Pressure in Elderly Adults.Journal of the American Heart Association · 2021Article
- Risk-Attributable Burden of Ischemic Heart Disease in 137 Low- and Middle-Income Countries From 2000 to 2019.Journal of the American Heart Association · 2021Article
- A randomized crossover trial of HEPA air filtration to reduce cardiovascular risk for near highway residents: Methods and approach.Contemporary clinical trials · 2021Article
- Development of a Job-Exposure Matrix for Ultrafine Particle Exposure: The MatPUF JEM.Annals of work exposures and health · 2021Review
- Health Lens Analysis: A Strategy to Engage Community in Environmental Health Research in Action.Sustainability · 2021Article
- Interaction between Long-Term Exposure to Fine Particulate Matter and Physical Activity, and Risk of Cardiovascular Disease and Overall Mortality in U.S. Women.Environmental health perspectives · 2020Article
- Two communities, one highway and the fight for clean air: the role of political history in shaping community engagement and environmental health research translation.BMC public health · 2020Article
- CBPR Partnerships and Near-Roadway Pollution: A Promising Strategy to Influence the Translation of Research into Practice.Environments (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundFew longitudinal studies have examined the association between ultrafine particulate matter (UFP, particles < 0.1 μm aerodynamic diameter) exposure and cardiovascular disease (CVD) risk factors. We used data from 791 adults participating in the longitudinal Boston Puerto Rican Health Study (Massachusetts, USA) between 2004 and 2015 to assess whether UFP exposure was associated with blood pressure and high sensitivity C-reactive protein (hsCRP, a biomarker of systemic inflammation).
methodsResidential annual average UFP exposure (measured as particle number concentration, PNC) was assigned using a model accounting for spatial and temporal trends. We also adjusted PNC values for participants' inhalation rate to obtain the particle inhalation rate (PIR) as a secondary exposure measure. Multilevel linear models with a random intercept for each participant were used to examine the association of UFP with blood pressure and hsCRP.
resultsOverall, in adjusted models, an inter-quartile range increase in PNC was associated with increased hsCRP (β = 6.8; 95% CI = - 0.3, 14.0%) but not with increased systolic blood pressure (β = 0.96; 95% CI = - 0.33, 2.25 mmHg), pulse pressure (β = 0.70; 95% CI = - 0.27, 1.67 mmHg), or diastolic blood pressure (β = 0.55; 95% CI = - 0.20, 1.30 mmHg). There were generally stronger positive associations among women and never smokers. Among men, there were inverse associations of PNC with systolic blood pressure and pulse pressure. In contrast to the primary findings, an inter-quartile range increase in the PIR was positively associated with systolic blood pressure (β = 1.03; 95% CI = 0.00, 2.06 mmHg) and diastolic blood pressure (β = 1.01; 95% CI = 0.36, 1.66 mmHg), but not with pulse pressure or hsCRP.
conclusionsWe observed that exposure to PNC was associated with increases in measures of CVD risk markers, especially among certain sub-populations. The exploratory PIR exposure metric should be further developed.
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