Evidence map›Paper›PMID 29621873›Full record

ArticleRadiation oncology journal2018

Set-up errors in head and neck cancer treated with IMRT technique assessed by cone-beam computed tomography: a feasible protocol.

Durim Delishaj, Stefano Ursino, Francesco Pasqualetti, Fabrizio Matteucci, Agostino Cristaudo, Carlo Pietro Soatti, Amelia Barcellini, Fabiola Paiar

Abstract read
In one paragraph

Article in Radiation oncology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Trial
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  9. Unmasking anxiety: a head-to-head comparison of open and closed masks in head and neck cancer radiotherapy.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
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  10. Article
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  13. Assessment of dosimetric impact of interfractional 6D setup error in tongue cancer treated with IMRT and VMAT using daily kV-CBCT.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023
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  14. Article
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  16. Impact of Cold Weather on Setup Errors in Radiotherapy.Journal of healthcare engineering · 2021
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  18. Dose distribution comparison in volumetric-modulated arc therapy plans for head and neck cancers with and without an external body contour extended technique.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Durim DelishajDepartment of Radiation Oncology, University Hospital Santa Chiara, Pisa, Italy.
Stefano UrsinoDepartment of Radiation Oncology, University Hospital Santa Chiara, Pisa, Italy.
Francesco PasqualettiDepartment of Radiation Oncology, University Hospital Santa Chiara, Pisa, Italy.
Fabrizio MatteucciDepartment of Radiation Oncology, University Hospital Santa Chiara, Pisa, Italy.
Agostino CristaudoDepartment of Radiation Oncology, University Hospital Santa Chiara, Pisa, Italy.
Carlo Pietro SoattiDepartment of Radiation Oncology, "A. Manzoni" Hospital, Lecco, Italy.
Amelia BarcelliniRadiotherapy Unit, IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Fabiola PaiarDepartment of Radiation Oncology, University Hospital Santa Chiara, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate set-up errors, suggest the adequate planning target volume (PTV) margin and image-guided radiotherapy frequency in head and neck (H&N) cancer treated with intensity-modulated radiotherapy (IMRT) assessed by kV cone-beam computed tomography (CBCT).

methodsWe analyzed 360 CBCTs in 60 patients with H&N cancer treated with IMRT. The target delineation was contoured according to ICRU62. PTVs were generated by adding a 3-5 mm margin in all directions to the respective clinical target volumes. The kV CBCT images were obtained at first three days of irradiation and weekly thereafter. The overall mean displacement, range, systematic (∑) and random (σ) errors were calculated. Adequate PTV margins were calculated according to the van Herk formula (2.5∑ + 0.7r).

resultsThe mean of set-up errors was less than 2 mm in any direction. The overall frequency of set-up displacements greater than 3 mm was 3.9% in medial-lateral (ML) direction, 8% in superior-inferior (SI) direction, and 15.5% in anterior-posterior (AP) direction. The range of translations shifts was 0-9 mm in ML direction, 0-5 mm in SI direction and 0-10 mm in AP direction, respectively. After systematic set-up errors correction, the adequate margin to overcome the problem of set-up errors was found to be less than 3 mm.

conclusionImage-guided kV CBCT was effective for the evaluation of set-up accuracy in H&N cancer. The kV CBCT at first three fractions and followed-by weekly appears adequate for reducing significantly set-up errors in H&N cancer treated with IMRT technique. Finally, 3-5 mm PTV margins appear adequate and safe to overcome the problem of set-up errors.

Indexed as

ChemotherapyCone-beam computed tomographyHead and neck cancerIMRT techniqueOncologyRadiotherapy

Identifiers

PMID29621873
PMCPMC5903362

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.