Evidence map›Paper›PMID 29621604›Full record

ArticleAnaerobe2018

Clostridioides difficile infection in dogs with chronic-recurring diarrhea responsive to dietary changes.

Rodrigo Otávio Silveira Silva, Carlos Augusto de Oliveira Júnior, Dominique S Blanc, Silvia Trindade Pereira, Mário Cesar Rennó de Araujo, Artur Vasconcelos, Francisco Carlos Faria Lobato

Abstract readCase Reports
In one paragraph

Article in Anaerobe, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. High genetic similarity betweenFrontiers in public health · 2025
    Article
  3. Article
  4. Prevalence ofAnimals : an open access journal from MDPI · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Rodrigo Otávio Silveira SilvaVeterinary School, Universidade Federal de Minas Gerais (UFMG), Antônio Carlos Avenue, 6627, Belo Horizonte, MG, 31.270-901, Brazil. Electronic address: rodrigo.otaviosilva@gmail.com.
Carlos Augusto de Oliveira JúniorVeterinary School, Universidade Federal de Minas Gerais (UFMG), Antônio Carlos Avenue, 6627, Belo Horizonte, MG, 31.270-901, Brazil.
Dominique S BlancService of Hospital Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland.
Silvia Trindade PereiraClínica Veterinária MedVet, Belo Horizonte, Brazil.
Mário Cesar Rennó de AraujoClínica Veterinária VetMaster, Belo Horizonte, Brazil.
Artur VasconcelosVeterinary School, Universidade Federal de Minas Gerais (UFMG), Antônio Carlos Avenue, 6627, Belo Horizonte, MG, 31.270-901, Brazil.
Francisco Carlos Faria LobatoVeterinary School, Universidade Federal de Minas Gerais (UFMG), Antônio Carlos Avenue, 6627, Belo Horizonte, MG, 31.270-901, Brazil.
Universidade Federal de Minas Gerais · BRFundação de Estudo e Pesquisa em Medicina Veterinária e Zootecnia · BRUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Five dogs with chronic-recurring diarrhea were positive for Clostridioides difficile infection (CDI), but were unresponsive to treatment with metronidazole. One of these animals was subjected to a colonoscopy, which revealed eosinophilic infiltration of the colon. All five animals completely recovered after dietary changes. The present work suggests that CDI might occur in dogs with other intestinal alterations. In addition, this report suggests that dysbiosis should be considered in animals that have chronic-recurring diarrhea and test positive for C. difficile.

Indexed as

AnimalsAnti-Infective AgentsChronic DiseaseClostridioides difficileClostridium InfectionsColonColonoscopyDiarrheaDiet TherapyDog DiseasesDogsMetronidazoleTreatment OutcomeAnti-Infective AgentsMetronidazoleC. difficile infectionInflammatory bowel diseaseIntestinal dysbiosis

Identifiers

PMID29621604
PMCPMC7111076
OpenAlexW2795443622

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.