Evidence map›Paper›PMID 29621512›Full record

ArticleAmerican journal of ophthalmology2018

Evolution of Consecutive Descemet Membrane Endothelial Keratoplasty Outcomes Throughout a 5-Year Period Performed by Two Experienced Surgeons.

Silvia Schrittenlocher, Friederike Schaub, Deniz Hos, Sebastian Siebelmann, Claus Cursiefen, Björn Bachmann

Abstract read
PubMed Publisher
In one paragraph

Article in American journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Predictors of long-term graft survival after descemet membrane endothelial keratoplasty.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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  7. Review
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  16. Risk factors for intraocular pressure elevation following Descemet membrane endothelial keratoplasty in Asian patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  17. Article
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  19. Review
  20. The Cologne-Mecklenburg-Vorpommern DMEK Donor Study (COMEDOS) - design and review of the influence of donor characteristics on Descemet membrane endothelial keratoplasty (DMEK) outcome.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Review
4 · The record

Corrections and comments

  • Commented on by
    2019
5 · Who and what money

Authors and funding

6 authors.

Silvia SchrittenlocherDepartment of Ophthalmology, University of Cologne, Cologne, Germany. Electronic address: Silvia.Schrittenlocher@uk-koeln.de.
Friederike SchaubDepartment of Ophthalmology, University of Cologne, Cologne, Germany.
Deniz HosDepartment of Ophthalmology, University of Cologne, Cologne, Germany; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
Sebastian SiebelmannDepartment of Ophthalmology, University of Cologne, Cologne, Germany.
Claus CursiefenDepartment of Ophthalmology, University of Cologne, Cologne, Germany; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
Björn BachmannDepartment of Ophthalmology, University of Cologne, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the evolution of clinical outcomes of more than 1300 Descemet membrane endothelial keratoplasties (DMEKs) alone or in combination with cataract surgery (triple DMEK) throughout a 5-year period at a single center, performed by 2 already experienced DMEK surgeons.

designRetrospective trend study.

methodsReview of charts between July 2011 and July 2016 at the Department of Ophthalmology, University of Cologne, Germany.

resultsA total of 1340 out of 1340 eyes with sufficient information were included. Six-month and 12-month best spectacle-corrected visual acuity (logMAR) had already reached high levels for the surgeries performed in 2011 (0.10 ± 0.06 and 0.09 ± 0.07, respectively) and did not further improve in later years (P = .272). Likewise, endothelial cell loss (ECL) and central corneal thickness (CCT) reached comparable levels independently of the year of surgery (average 12-month ECL was 38% ± 15% and average 6-month CCT decrease was 19% ± 11%). However, there was a decrease in the rebubbling rate, from 68% in 2011, 67% in 2012, and 70% in 2013 to 53% in 2014, 29% in 2015, and 16% in 2016, which was associated with the introduction of 20% sulfur hexafluoride (SF

conclusionsAfter an initial learning curve in DMEK surgery, results of visual acuity and ECL do not seem to further improve. However, the complication rate continuously declines, at least over the subsequent 5-year period analyzed herein.

Indexed as

Cataract ExtractionLearning CurveAgedAged, 80 and overAnterior ChamberCorneal DiseasesCorneal Endothelial Cell LossCorneal PachymetryDescemet Stripping Endothelial KeratoplastyEndotamponadeEndothelium, CornealFemaleFuchs' Endothelial DystrophyGraft RejectionHumansIntraoperative ComplicationsSulfur Hexafluoride

Identifiers

PMID29621512

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.