Evidence map›Paper›PMID 29621378›Full record

Trial reportJAMA oncology2018

Oral Ketamine vs Placebo in Patients With Cancer-Related Neuropathic Pain: A Randomized Clinical Trial.

Marie T Fallon, Andrew Wilcock, Caroline A Kelly, James Paul, Liz-Anne Lewsley, John Norrie, Barry J A Laird

Registry-linked trialAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in JAMA oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05378555 (A Pilot Study of the Use of Oral Ketamine for Treatment of Vaso-Occlusive Pain in Adolescents and Young Adults), which is not on this map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05378555 phase3recruitingnot on this mapstarted 2023, after this paper: background citation

A Pilot Study of the Use of Oral Ketamine for Treatment of Vaso-Occlusive Pain in Adolescents and Young Adults

TypeinterventionalSponsorBoston Children's HospitalRan2023 to 2026Enrolled10ConditionsVaso-occlusive CrisisArmsKetamine Hydrochloride
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Infusion Therapy in the Treatment of Neuropathic Pain.Current pain and headache reports · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marie T FallonEdinburgh Cancer Research Centre (IGMM), University of Edinburgh, Edinburgh, United Kingdom.
Andrew WilcockFaculty of Medicine and Health Sciences, University of Nottingham, Nottingham, United Kingdom.
Caroline A KellyCancer Research UK Clinical Trials Unit, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.
James PaulCancer Research UK Clinical Trials Unit, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.
Liz-Anne LewsleyCancer Research UK Clinical Trials Unit, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.
John NorrieUsher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Barry J A LairdEdinburgh Cancer Research Centre (IGMM), University of Edinburgh, Edinburgh, United Kingdom.

Funding

Cancer Research UK 25355Marie Curie MCCC-RP-12-A14197
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAnalgesicsAntineoplastic AgentsAnxietyCancer PainCognition DisordersDepressionDouble-Blind MethodFatigueFemaleGastrointestinal DiseasesHumansKetamineMaleMiddle AgedNeuralgiaAnalgesicsAntineoplastic AgentsKetamine

Identifiers

PMID29621378
PMCPMC6145686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.