ArticlePloS one2018
Comprehensive haematological indices reference intervals for a healthy Omani population: First comprehensive study in Gulf Cooperation Council (GCC) and Middle Eastern countries based on age, gender and ABO blood group comparison.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Hematological parameters' reference intervals in apparently healthy individuals in Saudi Arabia: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Haematological and Biochemical Reference Values for Healthy Population of Maferinyah Rural Community in Guinea.BioMed research international · 2020Trial
- A Machine Learning Approach to Reference Interval Estimation for Red Cell Parameters in a South and East Asian Population.Annals of laboratory medicine · 2026Article
- Common Hematological Reference Indices Among Healthy Reproductive Age Indian Women-Data Subset from Nationwide Study.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024Article
- Derivation of Russian-specific reference intervals for complete blood count, iron markers and related vitamins.PloS one · 2024Article
- Determine Complete Blood Count Reference Values Among Healthy Adult Populations.Journal of blood medicine · 2024Article
- Blood count reference intervals for the Brazilian adult population: National Health Survey.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2023Article
- Establishment of reference intervals for hematological parameters of adult population in the western region of Saudi Arabia.PloS one · 2023Article
- Hematological indices reference intervals for a healthy Arab population in Qatar: Effect of age, gender, and geographic location.Medicine · 2022Article
- Prevalence of preoperative Deep Venous Thrombosis (DVT) following elderly intertrochanteric fractures and development of a risk prediction model.BMC musculoskeletal disorders · 2022Article
- Hematological indices in the adult saudi population: Reference intervals by gender, age, and region.Frontiers in medicine · 2022Article
- Routine clinical chemistry and haematological test reference intervals for healthy adults in the Bhutanese population.PloS one · 2022Article
- Hematological reference intervals for adult population of Dire Dawa town, East Ethiopia.PloS one · 2021Article
- Hematology Reference Intervals for Healthy Adults of the City of Sulaymaniyah, Iraq.International journal of general medicine · 2020Article
- Coagulation Factors in Mexican Children, Young Adults and Older Adults.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReference intervals for venous blood parameters differs with age, gender, geographic region, and ethnic groups. Hence local laboratory reference intervals are important to improve the diagnostic accuracy of health assessments and diseases. However, there have been no comprehensive published reference intervals established in Oman, the Gulf Cooperation Council or Middle Eastern countries. Hence, the aim of this study was to establish reference intervals for full blood count in healthy Omani adults.
methodsVenous blood specimens were collected from 2202 healthy individuals aged 18 to 69 years from January 2012 to April 2017, and analysed by Sysmex XS-1000i and Cell-Dyn Sapphire automated haematology analysers. Results were statistically analysed and compared by gender, age, and ABO blood group. The lower and upper reference limits of the haematology reference intervals were established at the 2.5th and 97.5th percentiles respectively.
resultsReference intervals were calculated for 17 haematology parameters which included red blood cell, white blood cell, and platelet parameters. Red blood cell (RBC), haemoglobin (HGB), haematocrit (HCT), platelet and platelet haematocrit counts of the healthy donors were significantly different between males and females at all ages (p < 0.05), with males having higher mean values of RBC, HGB and HCT than females. Other complete blood count parameters showed no significant differences between genders, age groups, instruments, or blood groups. Our study showed a lower haemoglobin limit for the normal reference interval in males and females than the currently used in Oman.
conclusionsData from this study established specific reference intervals which could be considered for general use in Oman. The differences in haematology reference intervals highlights the necessity to establish reference intervals for venous blood parameters among the healthy population in each country or at least in each region.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.