Evidence map›Paper›PMID 29621240›Full record

ReviewPLoS genetics2018

A genomic overview of the population structure of Salmonella.

Nabil-Fareed Alikhan, Zhemin Zhou, Martin J Sergeant, Mark Achtman

Abstract readReview
In one paragraph

Review in PLoS genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 338 papers.

0numbers the graph read from it
0cells of the map it votes in
338citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

338 citing papers in PubMed.

  1. Article
  2. Article
  3. Nationwide outbreak ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Analysis of the genetic and phylogenetic context ofApplied and environmental microbiology · 2026
    Article
  8. Article
  9. Large outbreak ofEpidemiology and infection · 2026
    Article
  10. Genomic Evidence of Multidrug-ResistantbioRxiv : the preprint server for biology · 2026
    Article
  11. Microbiology spectrum · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. The emergence of chromosomally locatedFrontiers in microbiology · 2026
    Article
  16. Article
  17. Cell surface (Amsterdam, Netherlands) · 2025
    Article
  18. Article
  19. mSphere · 2025
    Article
  20. Article

278 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nabil-Fareed AlikhanWarwick Medical School, University of Warwick, Coventry, United Kingdom.ORCID 0000-0002-1243-0767
Zhemin ZhouWarwick Medical School, University of Warwick, Coventry, United Kingdom.
Martin J SergeantWarwick Medical School, University of Warwick, Coventry, United Kingdom.ORCID 0000-0001-7264-2668
Mark AchtmanWarwick Medical School, University of Warwick, Coventry, United Kingdom.ORCID 0000-0001-6815-0070

Funding

Biotechnology and Biological Sciences Research Council BB/L020319/1Wellcome Trust
6 · The paper itself

Abstract

For many decades, Salmonella enterica has been subdivided by serological properties into serovars or further subdivided for epidemiological tracing by a variety of diagnostic tests with higher resolution. Recently, it has been proposed that so-called eBurst groups (eBGs) based on the alleles of seven housekeeping genes (legacy multilocus sequence typing [MLST]) corresponded to natural populations and could replace serotyping. However, this approach lacks the resolution needed for epidemiological tracing and the existence of natural populations had not been independently validated by independent criteria. Here, we describe EnteroBase, a web-based platform that assembles draft genomes from Illumina short reads in the public domain or that are uploaded by users. EnteroBase implements legacy MLST as well as ribosomal gene MLST (rMLST), core genome MLST (cgMLST), and whole genome MLST (wgMLST) and currently contains over 100,000 assembled genomes from Salmonella. It also provides graphical tools for visual interrogation of these genotypes and those based on core single nucleotide polymorphisms (SNPs). eBGs based on legacy MLST are largely consistent with eBGs based on rMLST, thus demonstrating that these correspond to natural populations. rMLST also facilitated the selection of representative genotypes for SNP analyses of the entire breadth of diversity within Salmonella. In contrast, cgMLST provides the resolution needed for epidemiological investigations. These observations show that genomic genotyping, with the assistance of EnteroBase, can be applied at all levels of diversity within the Salmonella genus.

Indexed as

Databases, GeneticGenome, BacterialMultilocus Sequence TypingPhylogenyPolymorphism, Single NucleotideSalmonella

Identifiers

PMID29621240
PMCPMC5886390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.