Evidence map›Paper›PMID 29621181›Full record

ArticleInternational journal of molecular sciences2018

Dabrafenib Treatment in a Patient with an Epithelioid Glioblastoma and BRAF V600E Mutation.

Garry Ceccon, Jan-Michael Werner, Veronika Dunkl, Caroline Tscherpel, Gabriele Stoffels, Anna Brunn, Martina Deckert, Gereon R Fink, Norbert Galldiks

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Glioblastoma Therapy: Past, Present and Future.International journal of molecular sciences · 2024
    Review
  6. Review
  7. [Targeted Drug Therapy for Intracranial Tumors].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Clinicopathologic features and prognosis of epithelioid glioblastoma.International journal of clinical and experimental pathology · 2020
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Garry CecconDepartment of Neurology, University of Cologne, 50937 Cologne, Germany. garry.ceccon@uk-koeln.de.
Jan-Michael WernerDepartment of Neurology, University of Cologne, 50937 Cologne, Germany.
Veronika DunklDepartment of Neurology, University of Cologne, 50937 Cologne, Germany. veronika.dunkl@uk-koeln.de.
Caroline TscherpelDepartment of Neurology, University of Cologne, 50937 Cologne, Germany. caroline.tscherpel@uk-koeln.de.
Gabriele StoffelsInstitute of Neuroscience and Medicine (INM-3, -4), Forschungszentrum Juelich, 52425 Juelich, Germany. g.stoffels@fz-juelich.de.
Anna BrunnInstitute of Neuropathology, University of Cologne, 50937 Cologne, Germany. anna.brunn@uni-koeln.de.ORCID 0000-0001-6233-8339
Martina DeckertInstitute of Neuropathology, University of Cologne, 50937 Cologne, Germany. martina.deckert@uni-koeln.de.
Gereon R FinkDepartment of Neurology, University of Cologne, 50937 Cologne, Germany. gereon.fink@uk-koeln.de.
Norbert GalldiksDepartment of Neurology, University of Cologne, 50937 Cologne, Germany. n.galldiks@fz-juelich.de.
University of Cologne · DEForschungszentrum Jülich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel therapeutic targets in malignant glioma patients are urgently needed. Point mutations of the v-Raf murine sarcoma viral oncogene homolog B (

Indexed as

Antineoplastic AgentsChildFatal OutcomeGlioblastomaHumansImidazolesMaleMutationNeoplasm Recurrence, LocalOximesProto-Oncogene Proteins B-rafAntineoplastic AgentsdabrafenibImidazolesOximesProto-Oncogene Proteins B-rafBRAF inhibitorsepithelioid glioblastomatargeted therapyxanthoastrocytoma

Identifiers

PMID29621181
PMCPMC5979405
OpenAlexW2795842334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.