Evidence map›Paper›PMID 29621002›Full record

ArticleIEEE transactions on medical imaging2018

Penalized-Likelihood Reconstruction With High-Fidelity Measurement Models for High-Resolution Cone-Beam Imaging.

Steven Tilley, Matthew Jacobson, Qian Cao, Michael Brehler, Alejandro Sisniega, Wojciech Zbijewski, J Webster Stayman

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Evaluation of Fluence Reduction versus Sparsity for Diffusion Posterior Sampling Reconstruction in Low-Dose CT.Proceedings of SPIE--the International Society for Optical Engineering · 2026
    Article
  2. Joint CT reconstruction of anatomy and implants using a mixed prior model.Journal of medical imaging (Bellingham, Wash.) · 2025
    Article
  3. Multi-Material Decomposition Using Spectral Diffusion Posterior Sampling.IEEE transactions on bio-medical engineering · 2025
    Article
  4. CT Reconstruction using Nonlinear Diffusion Posterior Sampling with Detector Blur Modeling.Conference proceedings. International Conference on Image Formation in X-Ray Computed Tomography · 2024
    Article
  5. Article
  6. Diffusion Posterior Sampling for Nonlinear CT Reconstruction.Proceedings of SPIE--the International Society for Optical Engineering · 2024
    Article
  7. Article
  8. Three-material decomposition using a dual-layer flat panel detector in the presence of soft tissue motion.Proceedings of SPIE--the International Society for Optical Engineering · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. High-Resolution Model-based Material Decomposition for Multi-Layer Flat-Panel Detectors.Conference proceedings. International Conference on Image Formation in X-Ray Computed Tomography · 2020
    Article
  14. Article
  15. Model-based Material Decomposition with System Blur Modeling.Proceedings of SPIE--the International Society for Optical Engineering · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Steven Tilley
Matthew Jacobson
Qian Cao
Michael Brehler
Alejandro Sisniega
Wojciech Zbijewski
J Webster Stayman

Funding

Quantitative high resolution cone beam CT for assessment of bone and joint healthR01EB018896 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI ZBIJEWSKI, WOJCIECH BARTOSZ · 2014 to 2017
$2.0M
Incorporating Prior Knowledge of Surgical Devices in CBCT-Guided InterventionsR21EB014964 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI STAYMAN, JOSEPH WEBSTER · 2013 to 2014
$439k
Model-Based Reconstruction for High-Spatial Resolution Cone-Beam Computed TomographyF31EB023783 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI TILLEY, STEVEN WAYNE · 2017 to 2018
$85k
NIBIB NIH HHS F31 EB023783NIBIB NIH HHS R01 EB018896NIBIB NIH HHS R21 EB014964
6 · The paper itself

Abstract

We present a novel reconstruction algorithm based on a general cone-beam CT forward model, which is capable of incorporating the blur and noise correlations that are exhibited in flat-panel CBCT measurement data. Specifically, the proposed model may include scintillator blur, focal-spot blur, and noise correlations due to light spread in the scintillator. The proposed algorithm (GPL-BC) uses a Gaussian Penalized-Likelihood objective function, which incorporates models of blur and correlated noise. In a simulation study, GPL-BC was able to achieve lower bias as compared with deblurring followed by FDK as well as a model-based reconstruction method without integration of measurement blur. In the same study, GPL-BC was able to achieve better line-pair reconstructions (in terms of segmented-image accuracy) as compared with deblurring followed by FDK, a model-based method without blur, and a model-based method with blur but not noise correlations. A prototype extremities quantitative cone-beam CT test-bench was used to image a physical sample of human trabecular bone. These data were used to compare reconstructions using the proposed method and model-based methods without blur and/or correlation to a registered CT image of the same bone sample. The GPL-BC reconstructions resulted in more accurate trabecular bone segmentation. Multiple trabecular bone metrics, including trabecular thickness (Tb.Th.) were computed for each reconstruction approach as well as the CT volume. The GPL-BC reconstruction provided the most accurate Tb.Th. measurement, 0.255 mm, as compared with the CT derived value of 0.193 mm, followed by the GPL-B reconstruction, the GPL-I reconstruction, and then the FDK reconstruction (0.271 mm, 0.309 mm, and 0.335 mm, respectively).

Indexed as

AlgorithmsBone and BonesCone-Beam Computed TomographyHumansImage Processing, Computer-AssistedPhantoms, Imaging

Identifiers

PMID29621002
PMCPMC5889122

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.